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Protein-coding gene in humans
SUMO1/sentrin/SMT3 specific peptidase 3 , also known as SENP3 , is a protein which in humans is encoded by the SENP3 gene .[ 5] [ 6]
SENP3 together with SENP5, belongs to the Ulp1 branch in yeast and localize to nucleolus through B23/NPM1. SENP3 is associated and regulated by B23/nucleophosmin/NPM1 and involved in the regulation of ribosome biogenesis . SENP3 may be regulated by Arf-Mdm2-p53 pathway.[ 7]
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^ a b c GRCh38: Ensembl release 89: ENSG00000161956 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000005204 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Yeh ET, Gong L, Kamitani T (May 2000). "Ubiquitin-like proteins: new wines in new bottles". Gene . 248 (1–2): 1–14. doi :10.1016/S0378-1119(00)00139-6 . PMID 10806345 . ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs" . Genome Res . 11 (3): 422–35. doi :10.1101/gr.GR1547R . PMC 311072 PMID 11230166 . ^ "Entrez Gene: SENP3 SUMO1/sentrin/SMT3 specific peptidase 3" .
