SORBS3

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SORBS3
Protein SORBS3 PDB 2ct3.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SORBS3, SCAM-1, SCAM1, SH3D4, sorbin and SH3 domain containing 3
External IDs MGI: 700013 HomoloGene: 4218 GeneCards: SORBS3
RNA expression pattern
PBB GE SORBS3 209253 at fs.png

PBB GE SORBS3 207788 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001018003
NM_005775

NM_001271407
NM_001271408
NM_001271409
NM_011366

RefSeq (protein)

NP_001018003
NP_005766

NP_035496.1
NP_001258336
NP_001258337
NP_001258338
NP_035496

Location (UCSC) Chr 8: 22.54 – 22.58 Mb Chr 14: 70.18 – 70.21 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Vinexin is a protein that in humans is encoded by the SORBS3 gene.[3][4][5]


Interactions[edit]

SORBS3 has been shown to interact with DLG5[6] and MAPK1.[7]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Kioka N; Sakata S; Kawauchi T; Amachi T; Akiyama SK; Okazaki K; Yaen C; Yamada KM; Aota S (Mar 1999). "Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization". J Cell Biol. 144 (1): 59–69. doi:10.1083/jcb.144.1.59. PMC 2148117Freely accessible. PMID 9885244. 
  4. ^ Kioka N (Jan 2003). "[A novel adaptor protein family regulating cytoskeletal organization and signal transduction--Vinexin, CAP/ponsin, ArgBP2]". Seikagaku. 74 (11): 1356–60. PMID 12510380. 
  5. ^ "Entrez Gene: SORBS3 sorbin and SH3 domain containing 3". 
  6. ^ Wakabayashi, Makoto; Ito Takuya; Mitsushima Masaru; Aizawa Sanae; Ueda Kazumitsu; Amachi Teruo; Kioka Noriyuki (Jun 2003). "Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact". J. Biol. Chem. United States. 278 (24): 21709–14. doi:10.1074/jbc.M211004200. ISSN 0021-9258. PMID 12657639. 
  7. ^ Mitsushima, Masaru; Suwa Akira; Amachi Teruo; Ueda Kazumitsu; Kioka Noriyuki (Aug 2004). "Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin". J. Biol. Chem. United States. 279 (33): 34570–7. doi:10.1074/jbc.M402304200. ISSN 0021-9258. PMID 15184391. 

Further reading[edit]

External links[edit]