SRPRB

SRPRB
Identifiers
Aliases	SRPRB, APMCF1, SRP receptor beta subunit, SRP receptor subunit beta, SR-beta
External IDs	OMIM: 616883; MGI: 102964; HomoloGene: 6332; GeneCards: SRPRB; OMA:SRPRB - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	133,825,772 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	103,079,336 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; parotid gland; ; islet of Langerhans; ; cartilage tissue; ; tibia; ; epithelium of nasopharynx; ; stromal cell of endometrium; ; periodontal fiber; ; pericardium; ; corpus epididymis;
	Top expressed in
	saccule; ; otic placode; ; yolk sac; ; spermatocyte; ; renal corpuscle; ; neural layer of retina; ; otic vesicle; ; external carotid artery; ; parotid gland; ; internal carotid artery;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; signal recognition particle binding; GTP binding;
Cellular component	endoplasmic reticulum membrane; cytoplasmic microtubule; cytoplasm; integral component of membrane; signal recognition particle receptor complex; intracellular anatomical structure; endoplasmic reticulum; membrane;
Biological process	IRE1-mediated unfolded protein response;
	Sources:Amigo / QuickGO
Orthologs
	58477
	20818
	ENSG00000144867
	ENSMUSG00000032553
	Q9Y5M8
	P47758
	NM_021203; NM_001379313
	NM_009275
	NP_067026; NP_001366242
	NP_033301
	Wikidata
View/Edit Human	View/Edit Mouse

Signal recognition particle receptor subunit beta is a protein that in humans is encoded by the SRPRB gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000144867 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032553 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Miller JD, Tajima S, Lauffer L, Walter P (Mar 1995). "The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane". J Cell Biol. 128 (3): 273–82. doi:10.1083/jcb.128.3.273. PMC 2120348. PMID 7844142.
^ Legate KR, Falcone D, Andrews DW (Oct 2000). "Nucleotide-dependent binding of the GTPase domain of the signal recognition particle receptor beta-subunit to the alpha-subunit". J Biol Chem. 275 (35): 27439–46. doi:10.1074/jbc.M003215200. PMID 10859309.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: SRPRB signal recognition particle receptor, B subunit".