ST6GALNAC1

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ST6GALNAC1
Identifiers
Aliases ST6GALNAC1, HSY11339, SIAT7A, ST6GalNAcI, STYI, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
External IDs MGI: 1341826 HomoloGene: 7937 GeneCards: ST6GALNAC1
RNA expression pattern
PBB GE ST6GALNAC1 gnf1h06524 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001289107
NM_018414

NM_011371

RefSeq (protein)

NP_001276036
NP_060884

NP_035501.2
NP_035501

Location (UCSC) Chr 17: 76.62 – 76.64 Mb Chr 11: 116.77 – 116.78 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 is an enzyme that in humans is encoded by the ST6GALNAC1 gene.[3]

References[edit]

Further reading[edit]

  • Lee YC, Kaufmann M, Kitazume-Kawaguchi S, Kono M, Takashima S, Kurosawa N, Liu H, Pircher H, Tsuji S (April 1999). "Molecular cloning and functional expression of two members of mouse NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2,6-sialyltransferase family, ST6GalNAc III and IV". The Journal of Biological Chemistry. 274 (17): 11958–67. doi:10.1074/jbc.274.17.11958. PMID 10207017. 
  • Ikehara Y, Kojima N, Kurosawa N, Kudo T, Kono M, Nishihara S, Issiki S, Morozumi K, Itzkowitz S, Tsuda T, Nishimura SI, Tsuji S, Narimatsu H (November 1999). "Cloning and expression of a human gene encoding an N-acetylgalactosamine-alpha2,6-sialyltransferase (ST6GalNAc I): a candidate for synthesis of cancer-associated sialyl-Tn antigens". Glycobiology. 9 (11): 1213–24. doi:10.1093/glycob/9.11.1213. PMID 10536037. 
  • Donadio S, Dubois C, Fichant G, Roybon L, Guillemot JC, Breton C, Ronin C (2004). "Recognition of cell surface acceptors by two human alpha-2,6-sialyltransferases produced in CHO cells". Biochimie. 85 (3-4): 311–21. doi:10.1016/S0300-9084(03)00080-4. PMID 12770770. 
  • Julien S, Krzewinski-Recchi MA, Harduin-Lepers A, Gouyer V, Huet G, Le Bourhis X, Delannoy P (2003). "Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA". Glycoconjugate Journal. 18 (11-12): 883–93. doi:10.1023/A:1022200525695. PMID 12820722. 
  • Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (October 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Research. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697Freely accessible. PMID 12975309. 
  • Sewell R, Bäckström M, Dalziel M, Gschmeissner S, Karlsson H, Noll T, Gätgens J, Clausen H, Hansson GC, Burchell J, Taylor-Papadimitriou J (February 2006). "The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer". The Journal of Biological Chemistry. 281 (6): 3586–94. doi:10.1074/jbc.M511826200. PMID 16319059. 
  • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.