Maldonado was born in Jalapa, Veracruz, Mexico to Mario Maldonado and Sara Fuentes. She has two older brothers, Mario and Jesús and one sister, Fabiola. She studied acting in Centro de Educación Artística of Televisa for 2 years. Maldonado also studied English and acting while living in Vancouver, British Columbia, Canada in 2004. Maldonado participated in the Mexican beauty contest "El Rostro del Heraldo", which was organized by Mexican newspaper "El Heraldo", and won first place.
She debuted as the protagonist of the Mexican soap El Juego de la Vida (2001) in the role of Lorena "Lore" Alvarez. In the years 2002 and 2003, she participated in the teen angst soap opera Mexican hit Clase 406 in the role of Tatiana "Tatis" Del Moral. In April 2004, she was chosen again to the leading role of Diana Antillón De La Reguera in the soap Corazones al límite. She played the role of "Paulina Cervantes Bravo" in the Mexican soap opera "Mundo de Fieras". Starting in 2008, Maldonado played the lead role of "Aymar Mayu Lazcano" in another Mexican soap opera Tormenta En El Paraiso.
From November 2010 to March 2011, she played the title role in Aurora for the first 103 episodes, before her character was killed off. She also has a part La Reina del Sur (2011) as 'La Veronica'. She will be starring in Argos' newest telenovela El Octavo Mandamiento as Camila San Millán (Main Heroine) between 2011-2012.