Second-generation antidepressant

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Second-generation antidepressant
Drug class
Class identifiers
Use Depressive disorders
External links
MeSH D018687
In Wikidata

The second-generation antidepressants are a class of antidepressants characterized primarily by the era of their introduction, approximately coinciding with the 1970s and 1980s, rather than by their chemical structure or by their pharmacological effect. As a consequence, there is some controversy over which treatments actually belong in this class.

The term "third generation antidepressant" is sometimes used to refer to newer antidepressants,[1] from the 1990s and 2000s, often selective serotonin reuptake inhibitors (SSRIs) such as; fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft), as well as some non-SSRI antidepressants such as mirtazapine, nefazodone, venlafaxine, duloxetine and reboxetine. However, this usage is not universal.

Examples[edit]

This list is not exhaustive, and different sources vary upon which items should be considered second-generation.

See also[edit]

References[edit]

  1. ^ Olver JS, Burrows GD, Norman TR (2001). "Third-generation antidepressants: do they offer advantages over the SSRIs?". CNS Drugs. 15 (12): 941–54. PMID 11735614. doi:10.2165/00023210-200115120-00004. 

External links[edit]