Nialamide

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Nialamide
Nialamide.svg
Systematic (IUPAC) name
N-benzyl-3-(N'-(pyridine-4-carbonyl)hydrazino)propanamide
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
Legal status
Legal status
  • AU: S4 (Prescription only)
Identifiers
CAS Number 51-12-7 YesY
ATC code N06AF02 (WHO)
PubChem CID 4472
DrugBank DB04820 YesY
ChemSpider 4317 YesY
UNII T2Q0RYM725 YesY
KEGG D07337 YesY
Chemical data
Formula C16H18N4O2
Molar mass 298.34 g/mol
  (verify)

Nialamide (Niamid, Niamide, Nuredal, Surgex) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant.[1] It was withdrawn by Pfizer several decades ago due to the risk of hepatotoxicity.[2][3]

The antiatherogenic activity of nialamide was used to design pyridinolcarbamate.[4]

See also[edit]

References[edit]