TEP1

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TEP1
Identifiers
Aliases TEP1, TLP1, TP1, TROVE1, VAULT2, p240, telomerase associated protein 1
External IDs MGI: 109573 HomoloGene: 5157 GeneCards: 7011
RNA expression pattern
PBB GE TEP1 205727 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007110
NM_001319035

NM_009351

RefSeq (protein)

NP_009041.2

NP_033377.1

Location (UCSC) Chr 14: 20.37 – 20.41 Mb Chr 14: 50.82 – 50.87 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Telomerase protein component 1 is an enzyme that in humans is encoded by the TEP1 gene.[1][2]

This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans.[2] It is also a minor vault protein.

References[edit]

  1. ^ Saito T, Matsuda Y, Suzuki T, Hayashi A, Yuan X, Saito M, Nakayama J, Hori T, Ishikawa F (Jan 1998). "Comparative gene mapping of the human and mouse TEP1 genes, which encode one protein component of telomerases". Genomics 46 (1): 46–50. doi:10.1006/geno.1997.5005. PMID 9403057. 
  2. ^ a b "Entrez Gene: TEP1 telomerase-associated protein 1". 

Further reading[edit]