TLE2

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TLE2
Identifiers
Aliases TLE2, ESG, ESG2, GRG2, transducin like enhancer of split 2
External IDs MGI: 104635 HomoloGene: 20693 GeneCards: TLE2
RNA expression pattern
PBB GE TLE2 204431 at fs.png

PBB GE TLE2 40837 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001144761
NM_001144762
NM_001300846
NM_003260

NM_001252401
NM_019725

RefSeq (protein)

NP_001138233
NP_001138234
NP_001287775
NP_003251

NP_062699.1
NP_001239330
NP_062699

Location (UCSC) Chr 19: 3 – 3.05 Mb Chr 10: 81.57 – 81.59 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Transducin-like enhancer protein 2 is a protein that in humans is encoded by the TLE2 gene.[3][4]


Interactions[edit]

TLE2 has been shown to interact with TLE1[5] and HES1.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Liu Y, Dehni G, Purcell KJ, Sokolow J, Carcangiu ML, Artavanis-Tsakonas S, Stifani S (Oct 1996). "Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia". Genomics. 31 (1): 58–64. doi:10.1006/geno.1996.0009. PMID 8808280. 
  4. ^ "Entrez Gene: TLE2 transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)". 
  5. ^ a b Grbavec, D; Lo R; Liu Y; Stifani S (Dec 1998). "Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy/Enhancer of split proteins, and is expressed during neuronal development". Eur. J. Biochem. GERMANY. 258 (2): 339–49. doi:10.1046/j.1432-1327.1998.2580339.x. ISSN 0014-2956. PMID 9874198. 

Further reading[edit]