TLL2

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TLL2
Identifiers
Aliases TLL2
External IDs MGI: 1346044 HomoloGene: 56545 GeneCards: TLL2
Genetically Related Diseases
attention deficit hyperactivity disorder[1]
RNA expression pattern
PBB GE TLL2 215008 at fs.png

PBB GE TLL2 215843 s at fs.png

PBB GE TLL2 208027 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012465

NM_011904

RefSeq (protein)

NP_036597

NP_036034.1
NP_036034

Location (UCSC) Chr 10: 96.36 – 96.51 Mb Chr 19: 41.08 – 41.21 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Tolloid-like protein 2 is a protein that in humans is encoded by the TLL2 gene.[4][5]

This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin.[5]

References[edit]

  1. ^ "Diseases that are genetically associated with TLL2 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Scott IC, Clark TG, Takahara K, Hoffman GG, Eddy RL, Haley LL, Shows TB, Greenspan DS (Oct 1999). "Assignment of TLL1 and TLL2, which encode human BMP-1/Tolloid-related metalloproteases, to chromosomes 4q32→q33 and 10q23→q24 and assignment of murine Tll2 to chromosome 19". Cytogenet Cell Genet. 86 (1): 64–5. doi:10.1159/000015412. PMID 10516436. 
  5. ^ a b "Entrez Gene: TLL2 tolloid-like 2". 

Further reading[edit]