TMF1

TMF1
Identifiers
Aliases	TMF1, ARA160, TMF, TATA element modulatory factor 1
External IDs	OMIM: 601126; MGI: 2684999; HomoloGene: 133801; GeneCards: TMF1; OMA:TMF1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	97,156,083 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; stromal cell of endometrium; ; caput epididymis; ; islet of Langerhans; ; bronchial epithelial cell; ; right uterine tube; ; corpus epididymis; ; rectum; ; body of pancreas; ; minor salivary glands;
	Top expressed in
	spermatid; ; otolith organ; ; spermatocyte; ; utricle; ; iris; ; secondary oocyte; ; ciliary body; ; pineal gland; ; conjunctival fornix; ; hand;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; transcription coregulator activity; protein binding;
Cellular component	cytoplasm; Golgi apparatus; membrane; Golgi membrane; endoplasmic reticulum; nucleus; cytosol;
Biological process	flagellated sperm motility; regulation of proteasomal protein catabolic process; male gonad development; regulation of transcription, DNA-templated; Leydig cell differentiation; positive regulation of cytokine production; cellular response to organic cyclic compound; negative regulation of apoptotic process; transcription by RNA polymerase II; negative regulation of gene expression; transcription, DNA-templated; positive regulation of testosterone secretion; defense response to bacterium; acrosome assembly; spermatid development; luteinizing hormone secretion; spermatid nucleus differentiation;
	Sources:Amigo / QuickGO
Orthologs
	7110
	232286
	n/a
	ENSMUSG00000030059
	P82094; Q6PII6
	B9EKI3
	NM_007114; NM_001363879
	NM_001081111
	NP_009045; NP_001350808; NP_009045.2
	NP_001074580
	Wikidata
View/Edit Human	View/Edit Mouse

TATA element modulatory factor is a protein that in humans is encoded by the TMF1 gene.^[4]^[5]

Template:PBB Summary

Interactions

TMF1 has been shown to interact with FER^[6] and Androgen receptor.^[7]

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030059 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Garcia JA, Ou SH, Wu F, Lusis AJ, Sparkes RS, Gaynor RB (Nov 1992). "Cloning and chromosomal mapping of a human immunodeficiency virus 1 "TATA" element modulatory factor". Proc Natl Acad Sci U S A. 89 (20): 9372–6. Bibcode:1992PNAS...89.9372G. doi:10.1073/pnas.89.20.9372. PMC 50133. PMID 1409643.
^ "Entrez Gene: TMF1 TATA element modulatory factor 1".
^ Schwartz, Y; Ben-Dor I; Navon A; Motro B; Nir U (Sep 1998). "Tyrosine phosphorylation of the TATA element modulatory factor by the FER nuclear tyrosine kinases". FEBS Lett. 434 (3). NETHERLANDS: 339–45. doi:10.1016/S0014-5793(98)01003-5. ISSN 0014-5793. PMID 9742951. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)
^ Hsiao, P W; Chang C (Aug 1999). "Isolation and characterization of ARA160 as the first androgen receptor N-terminal-associated coactivator in human prostate cells". J. Biol. Chem. 274 (32). UNITED STATES: 22373–9. doi:10.1074/jbc.274.32.22373. ISSN 0021-9258. PMID 10428808. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)CS1 maint: unflagged free DOI (link)

Interactions

References

Further reading