TRIM3

TRIM3
Identifiers
Aliases	TRIM3, BERP, HAC1, RNF22, RNF97, tripartite motif containing 3
External IDs	OMIM: 605493; MGI: 1860040; HomoloGene: 21290; GeneCards: TRIM3; OMA:TRIM3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	6,474,459 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	105,282,778 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; tibial nerve; ; right coronary artery; ; popliteal artery; ; ascending aorta; ; prefrontal cortex; ; canal of the cervix; ; ganglionic eminence; ; Brodmann area 10; ; left uterine tube;
	Top expressed in
	cerebellar cortex; ; superior frontal gyrus; ; cerebellar vermis; ; prefrontal cortex; ; piriform cortex; ; lateral geniculate nucleus; ; subiculum; ; pontine nuclei; ; hippocampus proper; ; habenula;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; protein C-terminus binding; protein binding; metal ion binding; ubiquitin protein ligase activity; ubiquitin-protein transferase activity;
Cellular component	cytoplasm; endosome; early endosome; intracellular anatomical structure; Golgi apparatus; dendrite; cell projection;
Biological process	protein transport; protein ubiquitination; nervous system development; protein polyubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	10612
	55992
	ENSG00000110171
	ENSMUSG00000036989
	O75382
	Q9R1R2
	NM_001248006; NM_001248007; NM_006458; NM_033278; NM_033279
	NM_001285870; NM_001285871; NM_001285873; NM_018880; NM_001360425
	NP_001234935; NP_001234936; NP_006449; NP_150594
	NP_001272799; NP_001272800; NP_001272802; NP_061368; NP_001347354
	Wikidata
View/Edit Human	View/Edit Mouse

Tripartite motif-containing protein 3 is a protein that in humans is encoded by the TRIM3 gene.^[5]^[6]

Template:PBB Summary

Interactions

TRIM3 has been shown to interact with Actinin alpha 4.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000110171 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036989 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ El-Husseini AE, Vincent SR (August 1999). "Cloning and characterization of a novel RING finger protein that interacts with class V myosins". J Biol Chem. 274 (28): 19771–7. doi:10.1074/jbc.274.28.19771. PMID 10391919.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: TRIM3 tripartite motif-containing 3".
^ El-Husseini, A E; Kwasnicka D; Yamada T; Hirohashi S; Vincent S R (January 2000). "BERP, a novel ring finger protein, binds to alpha-actinin-4". Biochem. Biophys. Res. Commun. 267 (3). UNITED STATES: 906–11. doi:10.1006/bbrc.1999.2045. ISSN 0006-291X. PMID 10673389. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

Interactions

References

Further reading