TRIM68

TRIM68
Identifiers
Aliases	TRIM68, GC109, RNF137, SS-56, SS56, tripartite motif containing 68
External IDs	OMIM: 613184; MGI: 2142077; HomoloGene: 9991; GeneCards: TRIM68; OMA:TRIM68 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	4,608,231 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	102,336,534 bp
RNA expression pattern
	Top expressed in
	palpebral conjunctiva; ; epithelium of bronchus; ; bronchial epithelial cell; ; prostate; ; gonad; ; right lobe of thyroid gland; ; glomerulus; ; metanephric glomerulus; ; parietal pleura; ; left lobe of thyroid gland;
	Top expressed in
	lumbar spinal ganglion; ; mucosa of urinary bladder; ; transitional epithelium of urinary bladder; ; genital tubercle; ; lobe of prostate; ; retinal pigment epithelium; ; mammary gland; ; Paneth cell; ; urethra; ; superior cervical ganglion;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; androgen receptor binding; histone acetyltransferase binding; metal ion binding; ubiquitin-protein transferase activity; transferase activity;
Cellular component	cytoplasm; perinuclear region of cytoplasm; Golgi apparatus; nucleolus; intracellular anatomical structure; nucleus; cytosol;
Biological process	interferon-gamma-mediated signaling pathway; regulation of androgen receptor signaling pathway; protein ubiquitination; protein autoubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	55128
	101700
	ENSG00000167333
	ENSMUSG00000073968
	Q6AZZ1
	Q8K243
	NM_018073; NM_001304496
	NM_198012; NM_001307998
	NP_001291425; NP_060543
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Tripartite motif-containing protein 68 is a protein that in humans is encoded by the TRIM68 gene.^[5]^[6]

Template:PBB Summary

Interactions

TRIM68 has been shown to interact with Androgen receptor.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167333 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000073968 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chang GT, Steenbeek M, Schippers E, Blok LJ, van Weerden WM, van Alewijk DC, Eussen BH, van Steenbrugge GJ, Brinkmann AO (Oct 2001). "A novel gene on human chromosome 2p24 is differentially expressed between androgen-dependent and androgen-independent prostate cancer cells". Eur J Cancer. 37 (16): 2129–34. doi:10.1016/S0959-8049(01)00259-3. PMID 11597395.
^ "Entrez Gene: TRIM68 tripartite motif-containing 68".
^ Miyajima, Naoto; Maruyama Satoru; Bohgaki Miyuki; Kano Satoshi; Shigemura Masahiko; Shinohara Nobuo; Nonomura Katsuya; Hatakeyama Shigetsugu (May 2008). "TRIM68 regulates ligand-dependent transcription of androgen receptor in prostate cancer cells". Cancer Res. 68 (9). United States: 3486–94. doi:10.1158/0008-5472.CAN-07-6059. PMID 18451177. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

Interactions

References

Further reading