Talk:Enoxaparin sodium

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Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Peer reviewers: Rduong16, Pharming16.

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References

Some references on the use of enoxaparin in MI:

PMID 15238590 - noninferior to UFH in high-risk ACS/NSTEMI
PMID 11092649 - use in high-TIMI score NSTEMI

JFW | T@lk 22:49, 26 July 2006 (UTC)[reply]

Fair use rationale for Image:Lovenox2.gif

Image:Lovenox2.gif is being used on this article. I notice the image page specifies that the image is being used under fair use but there is no explanation or rationale as to why its use in this Wikipedia article constitutes fair use. In addition to the boilerplate fair use template, you must also write out on the image description page a specific explanation or rationale for why using this image in each article is consistent with fair use.

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BetacommandBot (talk) 19:27, 2 January 2008 (UTC)[reply]

no sodium here

the drugbox information, as well as some of the actual article, omit the sodium ions presumably present in "enoxaparin sodium". That's normal, but it probably also means the article should be at enoxaparin rather than enoxaparin sodium.

Virtually all injectable drugs are likely to contain sodium and/or chloride ions to balance pH, so I'm not quite sure what's so specia —Preceding unsigned comment added by 188.46.182.225 (talk) 15:57, 13 March 2010 (UTC)[reply]

I agree! I think the article used to be called Enoxaparin. I also note the structure is missing sodiums - in fact it's missing quite a bit of the structure! I've drawn a new structure that includes sodiums, and I'll ask WP:PHARM to assist with cleanup. Walkerma (talk) 04:20, 12 December 2010 (UTC)[reply]

anti IIa activity

"enoxaparin preferentially potentiates the inhibition of coagulation factors Xa and IIa." i am shure this is wrong. the different of LMWH to UFH is that they only inhibit factor Xa because they are to short to form a complex of Xa and ATIII. Therefore they only inhibit factor Xa ant that is the reason why protamine sulfate can only reverse 66%of LMWH effect.. —Preceding unsigned comment added by 84.174.211.14 (talk) 20:34, 16 December 2010 (UTC)[reply]

Student Project

Hello all,

As part of an assignment in our health policy course several of my colleagues at UCSF School of Pharmacy and I will be looking through this article to see what we can contribute. My sandbox will be available for viewing and we welcome your feedback. We plan to work on the entire article. Yamahaguy's sandbox Yamahaguy17 (talk) 01:55, 3 November 2015 (UTC)[reply]

Summary of edits: Introduction: ensured all lines had citations. 1. Medical uses: rewrote section and added sources 1.1 Monitoring: updated 1.2 Reversal agent: updated 1.3 Pregnancy: rewrote section including redefinition of category and clarification on research 2. Side effects: categorized based on low and high incidence with citations and included citations on all others 3. Boxed warning: Added a “Boxed Warning” section describing the FDA’s most recent safety announcement for enoxaparin 4. Pharmacology: 4.1 MOA: rewrote this section with citations 4.2 PK: Added a “Pharmacokinetics” sub-section to the Pharmacology section to describe the ADME of enoxaparin 5. Drug class: Added a “Drug Class Section” to list similar drugs in the same class as enoxaparin 6. References: consolidated, removed if no longer applicable 7. External links: no changes Misc: added wiki links to related articles for key words Yamahaguy17 (talk) 17:12, 7 November 2015 (UTC)[reply]

Peer Review Edits

Overall, the enoxaparin sodium wiki page is very well done. Its concise and appears to provide all the necessary information with appropriate citations. A area of improvement that can be made is in the language used; some of the words in these sections are terms that individuals not in the health care industry may not understand. For example, what is anti-Xa mentioned in monitoring? How does this value relate to enoxaparin? Additionally one nice way for explanation of the mechanism of action can be a diagram or a picture of the clotting cascade and how it is inhibited.

All the sections here are important and relevant. The writing takes a neutral view of the drug. Nice work.

Per Mike, use "person" instead of "patient," and use "kidney" instead of "renal." — Preceding unsigned comment added by Pharming16 (talk • contribs) 03:41, 9 November 2015 (UTC)[reply]

Thank you for the feedback. Many of your suggestions have been incorporated. A clotting cascade diagram was not added however a link to the clotting cascade article was provided for readers. Thanks! Yamahaguy17 (talk) 19:43, 10 November 2015 (UTC)[reply]

External links modified

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Added archive https://web.archive.org/web/20151023072153/http://products.sanofi.us:80/lovenox/lovenox.html to http://products.sanofi.us/lovenox/lovenox.html

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I would think some statements could be better expressed

It seems to add explanation to link the 2 statements related to taking enoxaparin sodium by pregnant women could be better: "The multiple-dose vials of the brand name enoxaparin (Lovenox) contain 15 mg benzyl alcohol per 1 mL as a preservative." and ""Premature infants who have been given large amounts of benzyl alcohol (99–405 mg/kg/day) have experienced "gasping syndrome"." Also the statement "Although enoxaparin is used to prevent blood clots, pregnancy alone can raise a woman's risk of clotting.", there seems something was left unsaid. Can anybody help? ThomasYehYeh (talk) 08:50, 9 August 2024 (UTC)[reply]