Talk:Inferior olivary nucleus

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Needs much more info about climbing fibers and association with Purkinje cells of cerebellum! —Preceding unsigned comment added by (talk) 15:45, 5 January 2010 (UTC)


can someone put the function of the inferior olivary nucleus on here please?

I believe the function is not understood. As best I could figure out from reading on it is it integrates info from several sources and outputs to the inferior cerebellum pedunkle as powerful excitatory synapases on purkinje cells. I checked two different neuroanatomy texts. --Drewlew (talk) 21:52, 20 April 2008 (UTC)
After some more studying I'd say the inferior olive is in some capacity involved in unconscious coordinated movement based upon where it's inputs come from and where it's output goes. I can't find a source to say this or I'd add it to the page.--Drewlew (talk) 23:38, 20 April 2008 (UTC)

You can look in "Textbook of Medical Physiology" 11th edition by Guyton and Hall, pg. 703, under "Purkinje Cells 'Learn' to Correct Motor Erros-Role of the Climbing Fibers." The inferior olive is involved in "cerebellar learning." The process is not well understood, but basically it is believed to play a role in learning skills requiring dexterity. The first time you try something, you will mess up (not be perfect or precise), your muscles will send this feedback to the cerebellum (though probably through mossy fibers and not climbing fibers, the latter of which arise in the inferior olive). With training, there will be less correction required. This somehow is linked to climbing fibers, which arise in the inferior olive, and the stimulation they provide to the Purkinje cells. This stimulation is believed to lead to long-term modulation of the Purkinje cells, such that subsequent performance of said task will occur more smoothly and without as many mistakes.

I don't have time now to write this up and polish it for publication in wiki, but someone else is welcome to do it and to use my words wholesale if you want. -DDog99 —Preceding unsigned comment added by Ddog99 (talkcontribs) 22:50, 13 June 2008 (UTC)

could anyone tell me why both the inferior olivary and the dentate nuclei are like the folded lamina?Sina jose (talk) 08:19, 7 April 2010 (UTC)