Thalassiosira pseudonana

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Thalassiosira pseudonana
Scientific classification
Kingdom: Chromalveolata
Phylum: Heterokontophyta
Class: Coscinodiscophyceae
Order: Thalassiosirales
Family: Thalassiosiraceae
Genus: Thalassiosira
Species: T. pseudonana
Binomial name
Thalassiosira pseudonana
(Cleve, 1873)

Thalassiosira pseudonana is a species of marine centric diatom. It was chosen as the first eukaryotic marine phytoplankton for whole genome sequencing.[1] T. pseudonana was selected for this study because it is a model for diatom physiology studies, belongs to a genus widely distributed throughout the world's oceans, and has a relatively small genome at 34 mega base pairs. Scientists are researching on diatom light absorption, using the marine diatom of Thalassiosira. An engineered form of the diatom has been considered as a potential drug delivery vehicle for cancer treatment with chemotherapy drugs that are poorly soluble in water.[2]

The clone of T. pseudonana that was sequenced is CCMP 1335 and is available from the National Center for Marine Algae and Microbiota at Bigelow Laboratory for Ocean Sciences. This clone was originally collected in 1958 from Moriches Bay (Long Island, New York) and has been maintained continuously in culture.


  1. ^ Armbrust, E.; Berges, J.; Bowler, C.; Green, B.; Martinez, D.; Putnam, N.; Zhou, S.; Allen, A.; Apt, K.; Bechner, M.; Brzezinski, M. A.; Chaal, B. K.; Chiovitti, A.; Davis, A. K.; Demarest, M. S.; Detter, J. C.; Glavina, T.; Goodstein, D.; Hadi, M. Z.; Hellsten, U.; Hildebrand, M.; Jenkins, B. D.; Jurka, J.; Kapitonov, V. V.; Kröger, N.; Lau, W. W.; Lane, T. W.; Larimer, F. W.; Lippmeier, J. C.; Lucas, S. (2004). "The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism". Science 306 (5693): 79–86. Bibcode:2004Sci...306...79A. doi:10.1126/science.1101156. PMID 15459382. 
  2. ^

Further reading[edit]

Meksiarun, Phiranuphon; Spegazzini, Nicolas; Matsui, Hiroaki; Nakajima, Kensuke; Matsuda, Yusuke; Sato, Hidetoshi (January 2015). "In Vivo Study of Lipid Accumulation in the Microalgae Marine Diatom Thalassiosira pseudonana Using Raman Spectroscopy". Applied Spectroscopy 69 (1): 45–51. doi:10.1366/14-07598. 


Luo, Chun-Shan; Liang, Jun-Rong; Lin, Qun; Li, Caixia; Bowler, Chris; Anderson, Donald; Wang, Peng; Wang, Xin-Wei; Gao, Ya-Hui (Dec 2014). "Cellular Responses Associated with ROS Production and Cell Fate Decision in Early Stress Response to Iron Limitation in the Diatom Thalassiosira pseudonana". Journal of Proteome Research 13 (12): 5510-5523. doi:10.1021/pr5004664. 

Sunda, William G.; Shertzer, Kyle W.; Coggins, Lew (October 2014). "Positive feedbacks between bottom-up and top-down controls promote the formation and toxicity of ecosystem disruptive algal blooms: A modeling study". Elsevier Science 39: 342. doi:10.1016/j.hal.2014.09.005. 

Samukawa, Mio; Shen, Chen; Hopkinson, Brian; Matsuda, Yusuke (2014). "Localization of putative carbonic anhydrases in the marine diatom, Thalassiosira pseudonana" (PDF). Photosynthesis Research 121 (2-3): 235-249. doi:10.1007/s11120-014-9967-x. Retrieved 12 February 2015. 

Delalat, Bahman; Sheppard, Vonda C.; Ghaemi, Soraya Rasi; Rao, Shasha; Prestidge, Clive A.; McPhee, Gordon; Rogers, Mary-Louise; Donoghue, Jaqueline F.; Pillay, Vinochani; Johns, Terrance G.; Kroeger, Nils; Voelcker, Nicolas H. (2015). "Targeted drug delivery using genetically engineered diatom biosilica" (PDF). Nature Communications 6. doi:10.1038/ncomms9791. Retrieved 18 November 2015. 

  1. ^ Yi, Andy Xianliang; Leung, Priscilla T. Y.; Leung, Kenneth M. Y. (September 2014). "Photosynthetic and molecular responses of the marine diatom Thalassiosira pseudonana to triphenyltin exposure". AQUATIC TOXICOLOGY 154: 48–57. doi:10.1016/j.aquatox.2014.05.004.