Thymidine triphosphate

Thymidine triphosphate
	Space-filling model of the thymidine triphosphate molecule, 4- negative charge
Names
	IUPAC name [(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate
	Other names dTTP, 2'-deoxythymidine triphosphate
Identifiers
CAS Number	365-08-2 =;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL363559 ;
ChemSpider	58493 =;
ECHA InfoCard	100.006.064
IUPHAR/BPS	5505;
MeSH	thymidine+5'-triphosphate
PubChem CID	64968;
CompTox Dashboard (EPA)	DTXSID30189998 ;
	SMILES CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O;
Properties
Chemical formula	C10H17N2O14P3
Molar mass	482.168
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). (what is ?) Infobox references

Deoxythymidine triphosphate (dTTP) is one of the four nucleotide triphosphates that are used in the in vivo synthesis of DNA. Unlike the other deoxyribonucleotide triphosphates, thymidine triphosphate does not always contain the "deoxy" prefix in its name.^[1] The corresponding ribonucleoside triphosphate is called uridine triphosphate.

It can be used by DNA ligase to create overlapping "sticky ends" so that protruding ends of opened microbial plasmids may be closed up.

References

^ Coghill, Anne M.; Garson, Lorrin R., eds. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.

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[1] Coghill, Anne M.; Garson, Lorrin R., eds. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.

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