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Triethylammonium acetate

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Triethylammonium acetate
Names
IUPAC name
Triethylammonium acetate
Other names
teaa, triethylamine/acetate buffer
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.023.632 Edit this at Wikidata
  • InChI=1S/C6H15N.C2H4O2/c1-4-7(5-2)6-3;1-2(3)4/h4-6H2,1-3H3;1H3,(H,3,4) checkY
    Key: AVBGNFCMKJOFIN-UHFFFAOYSA-N checkY
  • InChI=1/C6H15N.C2H4O2/c1-4-7(5-2)6-3;1-2(3)4/h4-6H2,1-3H3;1H3,(H,3,4)
    Key: AVBGNFCMKJOFIN-UHFFFAOYAA
  • O=C(O)C.N(CC)(CC)CC
Properties
(CH3CH2)3NHOCOCH3
Molar mass 161.24 g/mol
Boiling point 164.5 °C (328.1 °F; 437.6 K)
Soluble
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Corrosive, harmful
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Triethylammonium acetate is a volatile buffering agent, which, when diluted in water, maintains pH at about 7. When mixed with other components, such as methanol or acetonitrile other pHs may be attained. It is used in the purification of DNA, for instance.

It is prepared from equimolar quantities of triethylamine and acetic acid. After the reaction requiring buffering is done, this buffer can easily be removed by freeze drying or some other evaporative method.

In a pure state, it is liquid at room temperature and it has a yellowish color. This compound tends to get oxidized during heating (observed as a darkening of the solution); thus, it is recommended to do so under a nitrogen blanket or purge.