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UBAP2

From Wikipedia, the free encyclopedia
UBAP2
Identifiers
AliasesUBAP2, UBAP-2, ubiquitin associated protein 2
External IDsMGI: 1916176; HomoloGene: 73649; GeneCards: UBAP2; OMA:UBAP2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020867
NM_001282529
NM_001282530
NM_018449

NM_026872

RefSeq (protein)

NP_081148

Location (UCSC)Chr 9: 33.92 – 34.05 MbChr 4: 41.19 – 41.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ubiquitin-associated protein 2 is a protein that in humans is encoded by the UBAP2 gene.[5][6]

Function

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This gene is a novel gene isolated based on its expression in the human adrenal gland. The full-length protein encoded by this gene contains a UBA-domain (ubiquitin associated domain), which is a motif found in several proteins having connections to ubiquitin and the ubiquitination pathway. In addition, the protein contains a region similar to a domain found in members of the atrophin-1 family. The function of this protein has not been determined. Additional alternate splice variants may exist, but their full length nature has not been determined.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000137073Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028433Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hofmann K, Bucher P (May 1996). "The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway". Trends in Biochemical Sciences. 21 (5): 172–3. doi:10.1016/S0968-0004(96)30015-7. PMID 8871400.
  6. ^ a b "Entrez Gene: UBAP2 ubiquitin associated protein 2".

Further reading

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