UBE1L

UBA7
Identifiers
Aliases	UBA7, D8, UBA1B, UBE1L, UBE2, ubiquitin like modifier activating enzyme 7, UBE7
External IDs	OMIM: 191325; MGI: 1349462; HomoloGene: 2502; GeneCards: UBA7; OMA:UBA7 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	49,813,953 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	107,861,259 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; spleen; ; right uterine tube; ; lymph node; ; appendix; ; duodenum; ; gallbladder; ; right ovary; ; left ovary; ; right lobe of thyroid gland;
	Top expressed in
	granulocyte; ; spleen; ; blood; ; duodenum; ; thymus; ; mesenteric lymph nodes; ; submandibular gland; ; jejunum; ; intestinal villus; ; ileum;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	ATP binding; ISG15 activating enzyme activity; nucleotide binding; ubiquitin-like modifier activating enzyme activity; ligase activity; protein binding; ubiquitin-protein transferase activity; ubiquitin activating enzyme activity;
Cellular component	nucleoplasm; cytosol; cytoplasm; nucleus;
Biological process	negative regulation of type I interferon production; ISG15-protein conjugation; protein ubiquitination; modification-dependent protein catabolic process; ubiquitin-dependent protein catabolic process; cellular response to DNA damage stimulus; protein modification by small protein conjugation;
	Sources:Amigo / QuickGO
Orthologs
	7318
	74153
	ENSG00000182179
	ENSMUSG00000032596
	P41226
	n/a
	NM_003335
	NM_023738
	NP_003326
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-like modifier-activating enzyme 7 is a protein that in humans is encoded by the UBA7 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182179 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032596 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kok K, Hofstra R, Pilz A, van den Berg A, Terpstra P, Buys CH, Carritt B (Aug 1993). "A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme". Proc Natl Acad Sci U S A. 90 (13): 6071–5. doi:10.1073/pnas.90.13.6071. PMC 46869. PMID 8327486.
^ "Entrez Gene: UBE1L ubiquitin-activating enzyme E1-like".

References

Further reading