UNC5C

UNC5C
Identifiers
Aliases	UNC5C, UNC5H3, unc-5 netrin receptor C
External IDs	OMIM: 603610; MGI: 1095412; HomoloGene: 2765; GeneCards: UNC5C; OMA:UNC5C - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	95,549,206 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	141,540,685 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; tibia; ; internal globus pallidus; ; pons; ; inferior ganglion of vagus nerve; ; subthalamic nucleus; ; testicle; ; right coronary artery; ; C1 segment; ; superior vestibular nucleus;
	Top expressed in
	genital tubercle; ; secondary oocyte; ; supraoptic nucleus; ; zygote; ; otic vesicle; ; ethmoid bone; ; suprachiasmatic nucleus; ; ascending aorta; ; cerebellar vermis; ; cribriform plate;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	netrin receptor activity; netrin receptor activity involved in chemorepulsion; protein binding; protein kinase binding; tubulin binding;
Cellular component	integral component of membrane; neuron projection; cell junction; plasma membrane; synapse; membrane; axon; dendrite; growth cone; neuronal cell body; lamellipodium; filopodium; cell surface; cell projection;
Biological process	positive regulation of apoptotic process; netrin-activated signaling pathway; multicellular organism development; brain development; regulation of cell migration; signal transduction; anterior/posterior axon guidance; axon guidance; apoptotic process; negative chemotaxis; chemorepulsion of axon; dorsal root ganglion development;
	Sources:Amigo / QuickGO
Orthologs
	8633
	22253
	ENSG00000182168
	ENSMUSG00000059921
	O95185
	O08747
	NM_003728
	NM_001293561; NM_009472
	NP_003719
	NP_001280490; NP_033498
	Wikidata
View/Edit Human	View/Edit Mouse

Netrin receptor UNC5C is a protein that in humans is encoded by the UNC5C gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182168 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000059921 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Leonardo ED, Hinck L, Masu M, Keino-Masu K, Ackerman SL, Tessier-Lavigne M (May 1997). "Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors". Nature. 386 (6627): 833–8. doi:10.1038/386833a0. PMID 9126742.
^ Ackerman SL, Knowles BB (Dec 1998). "Cloning and mapping of the UNC5C gene to human chromosome 4q21-q23". Genomics. 52 (2): 205–8. doi:10.1006/geno.1998.5425. PMID 9782087.
^ "Entrez Gene: UNC5C unc-5 homolog C (C. elegans)".

References

Further reading