USP15

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USP15
Protein USP15 PDB 1w6v.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases USP15, UNPH-2, UNPH4, ubiquitin specific peptidase 15
External IDs MGI: 101857 HomoloGene: 101542 GeneCards: USP15
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001252078
NM_001252079
NM_006313

NM_001301628
NM_027604

RefSeq (protein)

NP_001288557.1
NP_081880.2
NP_001288557
NP_081880

Location (UCSC) Chr 12: 62.26 – 62.42 Mb Chr 10: 123.11 – 123.2 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 15 is an enzyme that in humans is encoded by the USP15 gene.[3][4]

Ubiquitin (MIM 191339), a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs). Also see USP1 (MIM 603478).[supplied by OMIM][4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346. 
  4. ^ a b "Entrez Gene: USP15 ubiquitin specific peptidase 15". 

Further reading[edit]