User:Ank/sandbox

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Arthur M “Buzz” Brown
Arthur Brown
ChanTest's CEO Buzz Brown
Occupation(s)Founder, CEO, CSO
Alma materEmmanuel College, Cambridge
Known forCoining the phrase 'Big Bang'
Stellar nucleosynthesis theory
Hoyle's fallacy
B2FH paper
Hoyle-Narlikar theory
Steady state theory
Triple-alpha process
Panspermia
Awards
Scientific career
FieldsAstronomy
InstitutionsInstitute of Astronomy, Cambridge
Academic advisorsRudolf Peierls
Maurice Pryce
Philip Worsley Wood
Doctoral studentsJohn Moffat
Chandra Wickramasinghe
Cyril Domb
Jayant Narlikar
Leon Mestel
Peter Alan Sweet
Other notable studentsPaul C. W. Davies
Douglas Gough

Arthur M. “Buzz” Brown, M.D., Ph.D. is ChanTest’s founder, Executive Chairman & CSO, and an Adjunct Professor of Physiology and Biophysics at Case Western Reserve University, School of Medicine.

He is a trained cardiologist and physiologist with more than 30 years of experience in ion channels and their relationship to human disease and has published extensively in peer-reviewed journals.

Dr. Brown has established world-leading Physiology department at University of Texas Medical Branch, Baylor College of Medicine and Case Western Reserve University.


Early Life and education[edit]

Early career[edit]

Career[edit]

ChanTest[edit]

ChanTest logo created in 2009?.
ChanTest logo created in 2009?.

ChanTest company information needed here

ChanRX[edit]

ChanRX logo created in 2010?.
ChanRX logo created in 2010?.

ChanRX company information needed here

Honors and contributions[edit]

Dr. Brown’s honors include the following:

  • Recipient of the prestigious Distinguished Service Award by the Safety Pharmacology Society (SPS) in 2013 [2]
  • Established Investigator of the American Heart Association [3]
  • Javits Neuroscience Investigator Award [4]
  • The Harry B van Dyke Awards for Excellence in Medical Research (Pharmacology), Columbia University College of Physicians and Surgeons
  • American Physiological Society Water B. Cannon Lecturer
  • Recipient of American Heart Association Basic Research Prize
  • Recipient of Louis and Artur Lucian Award for Research in Circulatory Diseases
  • First Robert M. Berne Distinguished Lecturer of the American Physiological Society Cardiovascular Section [5]
  • Newton-Abraham Visiting Professor in Medical, Biological and Chemical Sciences, (MA Honors), University of Oxford, England

Major contributions from his research laboratories to the field of ion channels include:

  • Invention of ion-selective liquid exchanger microelectrodes [6] ;
  • Description of membrane–delimited G protein effects on ion channels [6] ;
  • Identification of the pore of voltage-gated and inwardly rectifying potassium channels [6] ;
  • Specification of hERG potassium channel as lethal target for non-cardiac drugs, e.g., Seldane, Propulsid, etc. [6]
  • Discovery of drug-induced block of hERG trafficking as cause of arrhythmias.


Dr. Brown is currently a collaborator with the US Federal Drug Administration (FDA) on cardiac safety issues. He holds nine patents on ion channel pharmacology, therapeutics and devices.

References[edit]

  1. ^ Cite error: The named reference frs was invoked but never defined (see the help page).
  2. ^ "2013 Distinguished Service Award Recipient". Retrieved 5 February 2014.
  3. ^ "The Rudy Clarenburg Lecture Series 1999". Retrieved 5 February 2014.
  4. ^ "College of Veterinary Medicine". Retrieved 5 February 2014.
  5. ^ "Recipients of the Robert M. Berne Distinguished Lectureship Award". Retrieved 5 February 2014.
  6. ^ a b c d Glaser, Vicki (2008 Dec). "An interview with Arthur M. "Buzz" Brown, M.D., Ph.D.". Assay and Drug Development Technologies. 6 (6): 737–42. doi:10.1089. PMID 19231939. {{cite journal}}: |access-date= requires |url= (help); Check |doi= value (help); Check date values in: |date= (help)

External links[edit]

Articles[edit]

Interviews[edit]