User:ChrisH2015/sandbox

This is the user sandbox of ChrisH2015. A user sandbox is a subpage of the user's user page. It serves as a testing spot and page development space for the user and is not an encyclopedia article. Create or edit your own sandbox here.

Other sandboxes: Main sandbox | Template sandbox

Finished writing a draft article? Are you ready to request review of it by an experienced editor for possible inclusion in Wikipedia? Submit your draft for review!

Neurogenic Factors

There are many neuroangiogenic factors. Some angiogenic factors act to promote neuronal growth and vice versa. The table shows some examples

Neuroangiogenic factor	Effect on neuron	Effect on vascular endothelial cells	Receptor/Ligand	Origin
IGF-1	Promotion of neurogenesis and synaptogenesis	EC proliferation, migration, and differentiation	Ligand	Liver cells
bFGF	Proliferation of cortical progenitors and neurogenesis	EC proliferation, migration, and differentiation	Ligand	Adipocytes
NGF	Neuron survival, differentiation	Promotion of angiogenesis and arteriogenesis in ischemic hindlimbs	Ligand	Multiple
Neuropilin	Axon guidance	Synergistic action of VEGF165 in EC migration and proliferation Vascular development	Receptor	Target cell
VEGF	Neuronal development and patterning, and has neurotrophic and neuroprotective effects	Induces angiogenesis, promotes endothelial cell survival, proliferation and migration	Ligand	Multiple