User:Irisissis/L31 Ribosomal Protein Leader

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Ribosomal L31 leader
Predicted secondary structure and sequence conservation of L31_leader. This picture was adapted from a previous publication. [1]
Identifiers
SymbolL31
Other data
RNA typeCis-reg; leader
Domain(s)Bacteria
PDB structuresPDBe

An L31 ribosomal protein leader is a ribosomal protein leader involved in ribosome biogenesis. It is used as an autoregulatory mechanism to control the concentration of the ribosomal protein L31. Five structurally distinct types of L31 ribosomal protein leader were predicted with a bioinformatic approach.[1] The structure is located in the 5′ untranslated regions of mRNAs encoding ribosomal protein L31 (rpmE),[1] and in one case L32 (rpmF). These are found in different species of Actinobacteria, Firmicutes or Gammaproteobacteria. The gammaproteobacterial type was also detected and validated in an independent experimental study using the organism Escherichia coli.[2]

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References[edit]

  1. ^ a b c Eckert, I; Weinberg, Z (24 May 2020). "Discovery of 20 novel ribosomal leader candidates in bacteria and archaea". BMC Microbiology. 20 (130). doi:10.1186/s12866-020-01823-6.{{cite journal}}: CS1 maint: unflagged free DOI (link) Cite error: The named reference "iris" was defined multiple times with different content (see the help page).
  2. ^ Aseev, LV; Koledinskaya, LS; Boni, IV (2 July 2020). "Autogenous regulation in vivo of the rpmE gene encoding ribosomal protein L31 (bL31), a key component of the protein-protein intersubunit bridge B1b". RNA. 26 (7). doi:10.1261/rna.074237.119.

External links[edit]

Category:Ribosomal protein leader