VPRBP

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DCAF1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases DCAF1, VPRBP, Vpr (HIV-1) binding protein, DDB1 and CUL4 associated factor 1, RIP
External IDs MGI: 2445220 HomoloGene: 8805 GeneCards: DCAF1
EC number 2.7.11.1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001015507

RefSeq (protein)

NP_001015507.1
NP_001015507

Location (UCSC) Chr 3: 51.4 – 51.5 Mb Chr 9: 106.82 – 106.88 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Protein VPRBP is a protein that in humans is encoded by the VPRBP gene.[3][4][5]


Interactions[edit]

VPRBP has been shown to interact with Merlin.[6]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Zhao LJ, Mukherjee S, Narayan O (Jun 1994). "Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein". J Biol Chem. 269 (22): 15577–82. PMID 8195203. 
  4. ^ Zhang S, Feng Y, Narayan O, Zhao LJ (Mar 2001). "Cytoplasmic retention of HIV-1 regulatory protein Vpr by protein-protein interaction with a novel human cytoplasmic protein VprBP". Gene. 263 (1-2): 131–40. doi:10.1016/S0378-1119(00)00583-7. PMID 11223251. 
  5. ^ "Entrez Gene: VPRBP Vpr (HIV-1) binding protein". 
  6. ^ Huang, J; Chen J (Jul 2008). "VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation". Oncogene. England. 27 (29): 4056–64. doi:10.1038/onc.2008.44. PMID 18332868. 

Further reading[edit]