WDR1

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WDR1
Identifiers
Aliases WDR1, AIP1, HEL-S-52, NORI-1, WD repeat domain 1
External IDs MGI: 1337100 HomoloGene: 6628 GeneCards: WDR1
RNA expression pattern
PBB GE WDR1 200611 s at fs.png

PBB GE WDR1 200609 s at fs.png

PBB GE WDR1 210935 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005112
NM_017491

NM_011715

RefSeq (protein)

NP_005103
NP_059830

NP_035845.1
NP_035845

Location (UCSC) Chr 4: 10.07 – 10.12 Mb Chr 5: 38.53 – 38.56 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

WD repeat-containing protein 1 is a protein that in humans is encoded by the WDR1 gene.[3][4]

This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Adler HJ, Winnicki RS, Gong TW, Lomax MI (May 1999). "A gene upregulated in the acoustically damaged chick basilar papilla encodes a novel WD40 repeat protein". Genomics. 56 (1): 59–69. doi:10.1006/geno.1998.5672. PMID 10036186. 
  4. ^ a b "Entrez Gene: WDR1 WD repeat domain 1". 

Further reading[edit]