WFDC1

WFDC1
Identifiers
Aliases	WFDC1, PS20, WAP four-disulfide core domain 1
External IDs	OMIM: 605322; MGI: 1915116; HomoloGene: 10920; GeneCards: WFDC1; OMA:WFDC1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	84,329,844 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	120,414,961 bp
RNA expression pattern
	Top expressed in
	saphenous vein; ; right coronary artery; ; seminal vesicula; ; retinal pigment epithelium; ; nipple; ; popliteal artery; ; tibial arteries; ; urethra; ; cardia; ; mucosa of urinary bladder;
	Top expressed in
	temporal muscle; ; muscle of thigh; ; triceps brachii muscle; ; skeletal muscle tissue; ; sternocleidomastoid muscle; ; digastric muscle; ; medial head of gastrocnemius muscle; ; soleus muscle; ; quadriceps femoris muscle; ; lens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase inhibitor activity; serine-type endopeptidase inhibitor activity; molecular function;
Cellular component	extracellular region; extracellular space;
Biological process	negative regulation of wound healing; negative regulation of peptidase activity; response to estradiol; negative regulation of inflammatory response; negative regulation of cell growth; regulation of cell growth; negative regulation of endopeptidase activity; negative regulation of epithelial cell proliferation;
	Sources:Amigo / QuickGO
Orthologs
	58189
	67866
	ENSG00000103175
	ENSMUSG00000023336
	Q9HC57
	Q9ESH5
	NM_001282466; NM_001282467; NM_021197
	NM_023395
	NP_001269395; NP_001269396; NP_067020
	NP_075884
	Wikidata
View/Edit Human	View/Edit Mouse

WAP four-disulfide core domain protein 1 is a protein that in humans is encoded by the WFDC1 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000103175 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023336 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Larsen M, Ressler SJ, Gerdes MJ, Lu B, Byron M, Lawrence JB, Rowley DR (Sep 2000). "The WFDC1 gene encoding ps20 localizes to 16q24, a region of LOH in multiple cancers". Mamm Genome. 11 (9): 767–73. doi:10.1007/s003350010135. PMID 10967136.
^ "Entrez Gene: WFDC1 WAP four-disulfide core domain 1".

References

Further reading