The Bills had a problematic quarterback situation, with former RedskinM.C. Reynolds, second-year Bills QB Johnny Green and ex-LionWarren Rabb all struggling at the passer position. None completed more than 46% of their passes, and only Reynolds had a winning record (2–1) and threw for more than 1,000 yards.
Punter Billy Atkins led the league in punts, with 85; he also led the league with 44.5 yards per punt. Atkins also played safety for the Bills in 1961, and led the league with 10 interceptions, and was 2nd-Team All-AFL on defense.
The Bills amassed a great deal of talent on their offensive line in the 1961 draft. Four of their first seven picks—Rice, Shaw, Barber and Bemiller, all offensive linemen—would go on to make at least one All-AFL team in the next five years. This draft would form the nucleus for the Bills' power running game over the next five years.