Trikala 2000 B.C. (alternate spelling: Trikalla), full name, Athlitikos Syllogos Trikala 2000 Basketball Club, was a Greek professional basketball club located in Trikala, Greece. The club was commonly known as either Trikala B.C., or Trikala 2000. Trikala competed in the Greek League, the top tier of Greek basketball.
The Athletic Association of Trikala 2000 was founded on September 13, 1999, following the merger of local Trikala teams Danaos and Sporting. The club had a rapid rise up the Greek basketball leagues. In 2002, just three years after they were founded, Trikala won promotion to the Greek B Basketball League. In 2006, they again won promotion, that time to the Greek A2 League. Just two years later, they completed their journey, by gaining promotion to the top Greek League, after winning the A2 League, during the 2007-08 season.
The team's first season in the top league in Greece was a relatively successful and dramatic one, as they safeguarded their survival in the league, in the last game of the season, on April 22, 2009. In October of 2010, the club bankrupted.