Gallium nitrate

From Wikipedia, the free encyclopedia
  (Redirected from Ganite)
Jump to: navigation, search
Gallium nitrate
Identifiers
CAS number 69365-72-6 YesY
PubChem 61635
ChEMBL CHEMBL1200983 N
Jmol-3D images Image 1
Properties
Molecular formula Ga(NO3)3
Molar mass 255.7377 g/mol
Hazards
EU classification Oxidising agent O Irritant Xi
R-phrases R8 R36/37/38
S-phrases S17 S26
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Gallium nitrate (brand name Ganite) is the gallium salt of nitric acid with the chemical formula Ga(NO3)3. It is a drug used to treat symptomatic hypercalcemia secondary to cancer. It works by preventing the breakdown of bone through the inhibition of osteoclast activity, thus lowering the amount of free calcium in the blood.[1][2] Gallium nitrate is also used to synthesize other gallium compounds.

Contents

[edit] Preparation

Gallium nitrate is commercially available as the hydrate. The nonahydrate may also be prepared by dissolving gallium in nitric acid, followed by recrystallization.[3] The structure of gallium nitrate nonahydrate has been determined by X-ray crystallography.[4]

[edit] See also

[edit] References

  1. ^ Gallium Nitrate monograph. Lexi-Comp Online, Lexi-Drugs Online, Lexi-Comp Inc. Hudson, OH. Available at: [1]. Accessed September 13th, 2008.
  2. ^ Ganite at drugs.com
  3. ^ Birnara, Christiana; Kessler, Vadim G.; Papaefstathiou, Giannis S. (2009). "Mononuclear gallium(III) complexes based on salicylaldoximes: Synthesis, structure and spectroscopic characterization". Polyhedron 28 (15): 3291. doi:10.1016/j.poly.2009.04.039. 
  4. ^ Hendsbee, Arthur; Pye, Cory; Masuda, Jason (2009). "Hexaaquagallium(III) trinitrate trihydrate". Acta Crystallographica E 65: i65. doi:10.1107/S1600536809028086. 

[edit] External links




Personal tools
Namespaces

Variants
Actions
Navigation
Interaction
Toolbox
Print/export
Languages