Activated April 15, 1958 as Marine Helicopter Transport Squadron 764, Organized Marine Corps Reserve (Aviation), Naval Air Station, Los Alamitos, California
Redesignated April 1, 1962 as Marine Medium Helicopter Squadron 764, Organized Marine Corps Reserve (Aviation), Marine Air Reserve Training Detachment, Marine Air Reserve Training Command, Naval Air Station, Los Alamitos, California
From 25 April - 25 June 2008, the squadron was part of Special Purpose Marine Air Ground Task Force 24 (SPMAGTF 24) on board the USS Boxer (LHD-4). During this deployment the squadron brought essential air-lift capability to operations in Guatemala, El Salvador and Peru which allowed the various medical and engineering work site professionals the ability to get ashore. They flew 43 missions, 83 flight hours and transported 877 passengers. The mission is part of the Partnership of the Americas (POA) 2008. POA is a United States Southern Command sponsored annual maritime engagement operation to enhance multinational cooperation and strengthen partnership among navies and allied nations throughout the Americas. On January 13, 2013, HMM-764 became the first Marine Corps Reserve squadron to transition to the MV-22B Osprey. The squadron officially redesignated to Marine Medium Tiltrotor Squadron 764 (VMM-764) and relocated to Marine Corps Air Station Miramar in San Diego, CA.