By late 2009, ridership had expanded 47 percent compared to the former line running along the same route prior to the completion of the Euclid Corridor project and the creation of the HealthLine. Five years within opening, the Healthline has generated $5.8 billion in development along Euclid Avenue, representing a return of $114 for each transit dollar invested. 
A HealthLine rapid transit vehicle stopping at a station
The HealthLine runs a fleet of 21 articulated DE60LFA-BRT vehicles, manufactured by New Flyer Industries, each with a seating capacity of 47 and able to accommodate 53 more standing up. The vehicles run on a diesel-electric hybrid motor system that produce 90% less emissions than regular buses. A low sulfur diesel engine (Caterpillar C-9)generates electrical power to run smaller electric motors mounted on each of the wheels. Each vehicle also has a GPS locator on board, which allows automated traffic signals to give the HealthLine buses priority at busy intersections, keeping them moving as much as possible. Three doors on each side of the vehicle make for fast and easy boarding and unboarding. However, as late as July 2010, the trip from East Cleveland to downtown during rush hour was more than 40 minutes – longer than the planned 33 minutes. This was due to traffic light timing and the 25 mph speed limit along most of the route. The speed limit was raised to 35 mph for buses and traffic light timing was adjusted further to combat this issue.
There are 59 stations along Euclid Avenue that serve the HealthLine. All stations are equipped with a fare card vending machine, 24-hour lighting and an emergency phone. An illuminated text display informs passengers of expected arrival times. Between Public Square and East 107th Street, all stations have raised platforms that align with the floor of the rapid transit vehicle, making for very easy boarding and alighting.