The Heart of the Universe is a means by which one can be "synchronized" with the "frequency" of the entirety of Marvels infinite multiverse, becoming one with all aspects - matter; energy and even ideals. When the Titan Thanos merged with the Heart he claimed he became the individual thoughts of each and every sentient being and "...the last breath of a dying woman". Due to Thanos' "experience" in channeling vast amounts of energy, such as that of the Cosmic Cube and the Infinity Gems he was capable of directly merging with the Heart which seemingly granted him the power of The One Above All. Unlike Thanos, Akhenaten who at a previous time had come into possession of the Heart had to rely on machinery to siphon off small portions of energy. The Heart of the Universe provides the user with total omnipotence, omnipresence, omniscience and omnibenevolence. The Heart of the Universe is a power infinitely beyond that of the Cosmic Cubes, Infinity Gems and Infinity Gauntlet, truly having no scope or limits to its power. It is implied that the Heart is the power of the One-Above-All itself.