Hexetidine

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Hexetidine
Systematic (IUPAC) name
1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidin-5-amine
Clinical data
AHFS/Drugs.com International Drug Names
Pregnancy cat. Not to be used by pregnant women.
Legal status OTC
Routes Topical (mouthwash)
Identifiers
CAS number 141-94-6 YesY
ATC code A01AB12
PubChem CID 3607
UNII 852A84Y8LS YesY
Chemical data
Formula C21H45N3 
Mol. mass 339.602 g/mol
 YesY (what is this?)  (verify)

Hexetidine (Latin: Hexetidinum) is an anti-bacterial and anti-fungal agent commonly used in both veterinary and human medicine. It is a local anesthetic, astringent and deodorant and has antiplaque effects.[1][2]

Hexetidine is the medicinal ingredient in Sterisol, which is labelled for the symptomatic treatment of streptococcal pharyngitis ('strep throat'), tonsillitis, pharyngitis, laryngitis, gingivitis, ulcerative stomatitis, oral thrush and Vincent's angina; postoperative hygiene following tonsillectomy, throat or oral surgery.

In the UK, hexetidine is the active ingredient in the medicated mouthwash branded Oraldene. In Canada, hexetidine is the active ingredient in the medicated mouthwash branded Steri/sol. This is produced by Mcneil, a division of Johnson & Johnson. Oraldene contains 0.1 g/100 ml of hexetidine. In some European countries, the gargle solution and mouth spray in bottles of 40 ml named Hexoral (by Mcneil) also contains 0.2% Hexetidine as its active compound. Hexetidine can also be found in the mouthwash Bactidol (by Mcneil) which is sold in many Asian countries.

Hexetidine

[edit] References

  1. ^ Kapić E, Becić F, Becić E (2002). "Hexetidine--an oral antiseptic". Med Arh 56 (1): 43–8. PMID 11917691. 
  2. ^ "Oraldene". NetDoctor.co.uk. July 8, 2004. http://www.netdoctor.co.uk/medicines/100001942.html. Retrieved 2007-04-03. 

[edit] External links


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