Rhombencephalon

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Rhombencephalon
EmbryonicBrain.svg
Diagram depicting the main subdivisions of the embryonic vertebrate brain. These regions will later differentiate into forebrain, midbrain and hindbrain structures.
Gray708.svg
Scheme of roof of fourth ventricle.
Identifiers
Gray's p.767
MeSH A08.186.211.132.810
NeuroNames hier-531
NeuroLex ID Rhombencephalon
Dorlands
/Elsevier
r_12/12709581
TA A14.1.03.002
FMA FMA:67687
Anatomical terms of neuroanatomy

The rhombencephalon or hindbrain is a developmental categorization of portions of the central nervous system in vertebrates. It includes the medulla, pons, and cerebellum. Together they support vital bodily processes.[1]

Rhombencephalon

The hindbrain can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh8-Rh1. Rostrally, the isthmus demarcates the boundary with the midbrain or mesencephalon.

A rare disease of the rhombencephalon—"rhombencephalosynapsis"—is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia.

The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure.[2]

Myelencephalon[edit]

Rhombomeres Rh8-Rh4 form the myelencephalon.

The myelencephalon forms the medulla oblongata in the adult brain; it contains:

Metencephalon[edit]

Rhombomeres Rh3-Rh1 form the metencephalon.

The metencephalon is composed of the pons and the cerebellum; it contains:

Evolution[edit]

The hindbrain is homologous to a part of the arthropod brain known as the sub-oesophageal ganglion, in terms of the genes that it expresses and its position in between the brain and the nerve cord.[3] On this basis, it has been suggested that the hindbrain first evolved in the Urbilaterian - the last common ancestor of chordates and arthropods - between 570 and 555 million years ago.[3][4]

Additional images[edit]

References[edit]

  1. ^ "Brain atlas - Hindbrain". Lundbeck Institute - Brain explorer. Retrieved 2013-06-04. 
  2. ^ SpringerLink - Journal Article
  3. ^ a b Ghysen A (2003). "The origin and evolution of the nervous system". Int. J. Dev. Biol. 47 (7–8): 555–62. PMID 14756331. 
  4. ^ Haycock, DE Being and Perceiving

External links[edit]