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CAS number 7512-17-6 YesY
PubChem 24139
ChemSpider 22563 YesY
UNII V956696549 N
Jmol-3D images Image 1
Molecular formula C8H15NO6
Molar mass 221.21
Melting point 211
S-phrases S24/25
Related compounds
Related Monosaccharides N-Acetylgalactosamine
Related compounds Glucosamine
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

N-Acetylglucosamine (N-acetyl-D-glucosamine, or GlcNAc, or NAG) is a monosaccharide derivative of glucose. It is an amide between glucosamine and acetic acid. It has a molecular formula of C8H15NO6, a molar mass of 221.21 g/mol, and it is significant in several biological systems.

It is part of a biopolymer in the bacterial cell wall, built from alternating units of GlcNAc and N-acetylmuramic acid (MurNAc), cross-linked with oligopeptides at the lactic acid residue of MurNAc. This layered structure is called peptidoglycan (formerly called murein).

GlcNAc is the monomeric unit of the polymer chitin, which forms the outer coverings of insects and crustaceans. It is the main component of the radulas of mollusks, the beaks of cephalopods, and a minor component of the cell walls of Fungi.

Polymerized with glucuronic acid, it forms hyaluronan.

Medical uses[edit]

It has been proposed as a treatment for autoimmune diseases,[1] and recent tests have claimed some success.[2]

See also[edit]


  1. ^ "Sugar supplement may treat immune disease - health - 07 June 2007 - New Scientist". Retrieved 2007-06-08. 
  2. ^ "Glucosamine-Like Supplement Suppresses Multiple Sclerosis Attacks, Study Suggests". Science Daily. 

External links[edit]