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Classification and external resources
ICD-10 M85.8, Q77.4
ICD-9 756.52
DiseasesDB 15823
NCI Osteosclerosis
MeSH D010026

Osteosclerosis, an elevation in bone density,[1] is normally detected on a radiograph as an area of increased opacity; that is, where more mineral is present in the bone to absorb or deflect the X-ray beam. Localized osteosclerosis can be caused by injuries that compress the bone, by osteoarthritis, and osteoma.

It is associated with:

It can also be associated with Hepatitis C.[2]


  1. ^ "Medcyclopaedia - Osteosclerosis". Archived from the original on 2012-02-05. Retrieved 2007-12-23. 
  2. ^ Fiore CE, Riccobene S, Mangiafico R, Santoro F, Pennisi P (2005). "Hepatitis C-associated osteosclerosis (HCAO): report of a new case with involvement of the OPG/RANKL system". Osteoporos Int 16 (12): 2180–4. doi:10.1007/s00198-005-1858-8. PMID 15983730.