Growth factor receptor

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A growth factor receptor is a receptor which binds to growth factor.^[1]

These receptors may use the JAK/STAT, MAP kinase, and PI3 kinase pathways.^[2]

[edit] References

^ MeSH Growth+Factor+Receptors
^ A. V. Hoffbrand; P. A. H. Moss; J. E. Pettit (2006). Essential haematology. Wiley-Blackwell. pp. 6–. ISBN 9781405136495. http://books.google.com/books?id=IFFL_1YNy_oC&pg=PA6. Retrieved 28 November 2010.

v t e Receptors: growth factor receptors

Type I cytokine receptor	Nerve growth factors: Ciliary neurotrophic factor Erythropoietin

Receptor protein serine/threonine kinase	TGF pathway: TGF-beta (1, 2) · Activin (1, 2) · Bone morphogenetic protein (1, 2)

Receptor tyrosine kinase	Fibroblast growth factor (1, 2, 3, 4) Nerve growth factors: high affinity Trk (TrkA, TrkB, TrkC) Hepatocyte growth factor Somatomedin (Insulin-like growth factor 1) ErbB/Epidermal growth factor VEGF (1, 2, 3)

Tumor necrosis factor receptor	Nerve growth factors: Low affinity/p75

Ig superfamily	Platelet-derived growth factor (A, B) Stem cell factor

Other/ungrouped	Somatomedin (Insulin-like growth factor 2)

B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)

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