Pinealoblastoma

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Pinealoblastoma
Classification and external resources
ICD-10 C75.3
ICD-O: 9362/3
MeSH D010871

Pineoblastoma (also pinealoblastoma) is a malignant tumor of the pineal gland. A pineoblastoma is a supratentorial midline primitive neuroectodermal tumor.

Pineoblastoma may occur in patients with hereditary uni- or bilateral retinoblastoma. When retinoblastoma patients present with pineoblastoma this is characterized as "trilateral retinoblastoma". [1] Prognosis of patients with trilateral retinoblastoma is dismal, only a few patients have survived more than 5 years after diagnosis; all survivors were diagnosed with small tumors in a subclinical stage.[2]

Lately, this disease was featured in headlines of several newspapers all over the world in a patient without retinoblatoma.[3]

References[edit]

  1. ^ Provenzale JM, Weber AL, Klintworth GK, McLendon RE (January 1995). "Radiologic-pathologic correlation. Bilateral retinoblastoma with coexistent pinealoblastoma (trilateral retinoblastoma)". AJNR Am J Neuroradiol 16 (1): 157–65. PMID 7900586. 
  2. ^ Kivelä T (June 1999). "Trilateral retinoblastoma: a meta-analysis of hereditary retinoblastoma associated with primary ectopic intracranial retinoblastoma". Journal of Clinical Oncology 17 (6): 1829–37. PMID 10561222. 
  3. ^ http://www.mirror.co.uk/news/uk-news/terminally-ill-schoolgirl-makes-miracle-3665979