Precancerous condition

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Precancerous condition
Classification and external resources
High-grade squamous intraepithelial lesion.jpg
Micrograph of high grade squamous intraepithelial lesion, a precancerous condition of the uterine cervix. Pap stain.
MeSH D011230

A precancerous condition (or premalignant condition) is a generalized state associated with an increased risk of cancer. If left untreated, these conditions may lead to cancer.

Premalignant lesion is a morphologically altered tissue in which cancer is more likely to occur than its apparently normal counterpart.

Examples of pre-malignant conditions include actinic keratosis,[1] Barrett's esophagus, atrophic gastritis, Dyskeratosis congenita, Sideropenic dysphagia, Lichen planus, Oral submucous fibrosis, Solar elastosis and cervical dysplasia.

Examples of pre-malignant lesions include Leukoplakia, Erythroplakia etc. Carcinoma in situ is a stage of tumour that is asessed as not yet cancer, though it has a high probability of becoming.

The term was coined in 1875 by Romanian physician Victor Babeş. After 2005 both the terms have been clubbed together and is now known as Potentially malignant lesions.


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