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In 2006 the European Sleep Apnea Database (ESADA) began as an initiative between 27 European sleep study facilities to combine information and compile it into one shared resource.<ref name="esrsmarch2013">''ESRS Newsletter'' 2013</ref><ref name="grote">Grote 2014</ref> It was formed as part of the [[European Cooperation in Science and Technology]] (COST) Action B 26.<ref name="europeanrespiratoryjournal" /><ref name="obesity">''Obesity, Fitness & Wellness Week'' 2011, p. 3.</ref> In addition to financial help from COST, the initiative received assistance from companies [[Respironics|Philips Respironics]] and [[ResMed]].<ref name="grotemay2012">Grote May 2012, pp. 10-11.</ref> The database storing the association's resource information is located in [[Gothenburg]], [[Sweden]].<ref name="grotemay2012" /> The group's goal was twofold: to serve as a reference guide to those researching sleep disorders, and to compile information about how different caregivers treat patients suffering from sleep apnea.<ref name="europeanrespiratoryjournal" /><ref name="obesity" />
In 2006 the European Sleep Apnea Database (ESADA) began as an initiative between 27 European sleep study facilities to combine information and compile it into one shared resource.<ref name="esrsmarch2013">''ESRS Newsletter'' 2013</ref><ref name="grote">Grote 2014</ref> It was formed as part of the [[European Cooperation in Science and Technology]] (COST) Action B 26.<ref name="europeanrespiratoryjournal" /><ref name="obesity">''Obesity, Fitness & Wellness Week'' 2011, p. 3.</ref> In addition to financial help from COST, the initiative received assistance from companies [[Respironics|Philips Respironics]] and [[ResMed]].<ref name="grotemay2012">Grote May 2012, pp. 10-11.</ref> The database storing the association's resource information is located in [[Gothenburg]], [[Sweden]].<ref name="grotemay2012" /> The group's goal was twofold: to serve as a reference guide to those researching sleep disorders, and to compile information about how different caregivers treat patients suffering from sleep apnea.<ref name="europeanrespiratoryjournal" /><ref name="obesity" />


5,103 patients were tracked from March 15, 2007 to August 1, 2009.<ref name="obesity" /> Data collected on these patients included symptoms suffered, medication, medical history, and sleep data, all inputted into an online format for further analysis.<ref name="obesity" /> Database researchers reported on their methodology and results in 2010 to the [[American Thoracic Society]], finding presentation of an increased percentage of both metabolic and cardiovascular problems in a study of patients with obstructive sleep apnea.<ref name="americanthoracicsociety">Hedner 2010</ref> The 2010 research resulted from collaboration between 22 study centres across 16 countries in Europe involving 27 researchers.<ref name="americanthoracicsociety" /> The primary participants who presented to the American Thoracic Society included researchers from: [[Sahlgrenska University Hospital]], [[Gothenburg]], [[Sweden]]; [[Technion – Israel Institute of Technology]], [[Haifa]], [[Israel]]; National TB & Lung Diseases Research Institute, [[Warsaw]], [[Poland]]; CNR Institute of Biomedicine and Molecular, [[Palermo]], [[Italy]]; Instituto Auxologico Italiano, Ospedale San Luca, [[Milan]], [[Italy]]; and St. Vincent University Hospital, [[Dublin]], [[Ireland]].<ref name="americanthoracicsociety" /> Their conclusions were published in 2010 in the ''[[American Journal of Respiratory and Critical Care Medicine]]''.<ref name="americanthoracicsociety" />
5,103 patients were tracked from March 15, 2007 to August 1, 2009.<ref name="obesity" /> Data collected on these patients included symptoms suffered, medication, medical history, and sleep data, all inputted into an online format for further analysis.<ref name="obesity" /> Database researchers reported on their methodology and results in 2010 to the [[American Thoracic Society]], on their observed findings regarding percentages of metabolic and cardiovascular impacts related to patients with obstructive sleep apnea.<ref name="americanthoracicsociety">Hedner 2010</ref> The 2010 research resulted from collaboration between 22 study centres across 16 countries in Europe involving 27 researchers.<ref name="americanthoracicsociety" /> The primary participants who presented to the American Thoracic Society included researchers from: [[Sahlgrenska University Hospital]], [[Gothenburg]], [[Sweden]]; [[Technion – Israel Institute of Technology]], [[Haifa]], [[Israel]]; National TB & Lung Diseases Research Institute, [[Warsaw]], [[Poland]]; CNR Institute of Biomedicine and Molecular, [[Palermo]], [[Italy]]; Instituto Auxologico Italiano, Ospedale San Luca, [[Milan]], [[Italy]]; and St. Vincent University Hospital, [[Dublin]], [[Ireland]].<ref name="americanthoracicsociety" /> Their results were published in 2010 in the ''[[American Journal of Respiratory and Critical Care Medicine]]''.<ref name="americanthoracicsociety" />


===2011 - present===
===2011 - present===
In 2011 there were 22 sleep disorder centres in [[Europe]] involved in the collaboration.<ref name="europeanrespiratoryjournal" /><ref name="obesity" /> The group published research in 2011 finding a significant percentage of patients suffering from sleep apnea have [[obesity]].<ref name="obesity" /> By 2012 the database maintained information on over 12,500 patients in Europe; it also contained [[DNA sample]]s of 2,600 individuals.<ref name="grotemay2012" /> ESADA was represented in 2012 at the 21st annual meeting of the European Sleep Research Society in [[Paris]], [[France]], and was one of four European Sleep Research Networks that held a session at the event.<ref name="esrs2012">''ESRS Newsletter'' 2012, p. 8.</ref> Pierre Escourrou and Fadia Jilwan wrote in a 2012 article for the ''[[European Respiratory Journal]]'' that after studying data from ESADA involving 8,228 total patients from 23 different facilities, they found [[polysomnography]] to be a good measure for [[hypopnea]] and sleep apnea.<ref name="escourrou">Escourrou 2012</ref> Researchers from the department of [[pulmonary disease]]s at [[Turku University Hospital]] in [[Turku]], [[Finland]] compared variations between sleep centres in the ESADA database and published their findings in the ''European Respiratory Journal''.<ref name="saaresranta">Saaresranta 2012</ref> They looked at the traits of 5,103 patients from 22 centres and found an average age of 51.8 years in ESADA, and varying methodology of performing sleep study with cardiorespiratory polygraphy predominant in the northern-most region.<ref name="saaresranta" />
In 2011 there were 22 sleep disorder centres in [[Europe]] involved in the collaboration.<ref name="europeanrespiratoryjournal" /><ref name="obesity" /> The group published research in 2011 on the percentage of patients suffering from sleep apnea that have [[obesity]].<ref name="obesity" /> By 2012 the database maintained information on over 12,500 patients in Europe; it also contained [[DNA sample]]s of 2,600 individuals.<ref name="grotemay2012" /> ESADA was represented in 2012 at the 21st annual meeting of the European Sleep Research Society in [[Paris]], [[France]], and was one of four European Sleep Research Networks that held a session at the event.<ref name="esrs2012">''ESRS Newsletter'' 2012, p. 8.</ref> Pierre Escourrou and Fadia Jilwan wrote a 2012 article for the ''[[European Respiratory Journal]]'' after studying data from ESADA involving 8,228 total patients from 23 different facilities.<ref name="escourrou" /> They analyzed whether [[polysomnography]] was a good measure for [[hypopnea]] and sleep apnea.<ref name="escourrou">Escourrou 2012</ref> Researchers from the department of [[pulmonary disease]]s at [[Turku University Hospital]] in [[Turku]], [[Finland]] compared variations between sleep centres in the ESADA database and published their findings in the ''European Respiratory Journal''.<ref name="saaresranta">Saaresranta 2012</ref> They looked at the traits of 5,103 patients from 22 centres.<ref name="saaresranta" /> They reported on the average age of patients in the database, and the prevalence by region of performing sleep study with cardiorespiratory polygraphy.<ref name="saaresranta" />


The database added a centre in [[Hamburg, Germany]] in 2013 managed by [[physician]] Holger Hein.<ref name="grote" /> The group's annual meeting in 2013 was held in [[Edinburgh]], [[United Kingdom]] and was ran by Renata Riha.<ref name="grote" /> By March 2013, there were approximately 13,000 total patients being studied in the program, with about 200 additional patients being added into the database each month.<ref name="esrsmarch2013" /> Analysis published by researchers from Italy and Sweden in September 2013 in the ''European Respiratory Journal'' documented a correlation between [[renal function]] problems and obstructive sleep apnea.<ref name="marrone">Marrone 2013</ref> They analyzed data from 17 countries in Europe representing 24 sleep centres and 8,112 total patients.<ref name="marrone" /> They found that patients who were older in age range, women, and had other existing health problems had higher chance of kidney function problems if they concurrently suffered from obstructive sleep apnea.<ref name="marrone" />
The database added a centre in [[Hamburg, Germany]] in 2013 managed by [[physician]] Holger Hein.<ref name="grote" /> The group's annual meeting in 2013 was held in [[Edinburgh]], [[United Kingdom]] and was ran by Renata Riha.<ref name="grote" /> By March 2013, there were approximately 13,000 total patients being studied in the program, with about 200 additional patients being added into the database each month.<ref name="esrsmarch2013" /> Analysis published by researchers from Italy and Sweden in September 2013 in the ''European Respiratory Journal'' analyzed if there was a correlation between [[renal function]] problems and obstructive sleep apnea.<ref name="marrone">Marrone 2013</ref> They analyzed data from 17 countries in Europe representing 24 sleep centres and 8,112 total patients.<ref name="marrone" /> They tested whether patients of different types of demographics with other existing health problems had higher chance of kidney function problems, if they concurrently suffered from obstructive sleep apnea.<ref name="marrone" />


In 2014, researchers released data studying 5,294 patients from the database and were able to correlate sleep apnea with increased [[blood sugar]].<ref name="healthcarepurchasing">''Healthcare Purchasing News'' 2014, p. 16.</ref> Their results were published in the ''European Respiratory Journal''.<ref name="rightvision">''Right Vision News'' 2014</ref><ref name="dailythepak">''Daily The Pak Banker'' 2014</ref> They studied [[glycated hemoglobin]] levels in the patients and compared them with measured severity in sleep apnea.<ref>''The Huffington Post'' 2014</ref> The researchers found that glycated hemoglobin levels increased by 5.24 percent among a class of individuals with less severe sleep apnea and 5.50 percent in the class with the highest determined amount of sleep apnea problems.<ref name="healthcarepurchasing" /> As of 20 March 2014 the database included information on a total of 15,956 patients.<ref name="grote" /> A 2014 article in the ''European Respiratory Journal'' drawing from the ESADA found that lack of adequate oxygen during a night's sleep was an indicator for [[high blood pressure]].<ref>Tkacova 2014, pp. 931-941</ref>
In 2014, researchers released data studying 5,294 patients from the database compared prevalence of sleep apnea with increased [[blood sugar]].<ref name="healthcarepurchasing">''Healthcare Purchasing News'' 2014, p. 16.</ref> Their results were published in the ''European Respiratory Journal''.<ref name="rightvision">''Right Vision News'' 2014</ref><ref name="dailythepak">''Daily The Pak Banker'' 2014</ref> They studied [[glycated hemoglobin]] levels in the patients and compared them with measured severity in sleep apnea.<ref>''The Huffington Post'' 2014</ref> The researchers analyzed glycated hemoglobin levels among a class of individuals with less severe sleep apnea and those with a higher determined amount of sleep apnea problems.<ref name="healthcarepurchasing" /> As of 20 March 2014 the database included information on a total of 15,956 patients.<ref name="grote" /> A 2014 article in the ''European Respiratory Journal'' drawing from the ESADA analyzed whether lack of adequate oxygen during a night's sleep was an indicator for [[high blood pressure]].<ref>Tkacova 2014, pp. 931-941</ref>


==Reception==
==Reception==

Revision as of 00:14, 25 October 2014

European Sleep Apnea Database
Formation2006
TypeCollaborative database
Legal statusActive
PurposeCompile information about sleep apnea
FieldsMedicine, Internal medicine, Sleep medicine, Sleep apnea
Key people
Jan Hedner
AffiliationsEuropean Cooperation in Science and Technology
Sahlgrenska Academy at Gothenburg University
WebsiteOfficial website

The European Sleep Apnea Database (ESADA) (also referred to with spelling European Sleep Apnoea Database[1][2] and European Sleep Apnoea Cohort[3][4]) is a collaboration between European sleep centres as part of the European Cooperation in Science and Technology (COST) Action B 26. The main contractor of the project is the Sahlgrenska Academy at Gothenburg University, Institute of Medicine, Department of Internal Medicine, and the co-ordinator is Jan Hedner, MD, PhD, Professor of Sleep Medicine.[2]

The book Clinical Genomics: Practical Applications for Adult Patient Care said ESDADA was an example of the kind of initiative which affords an "excellent opportunity" for future collaborative research into genetic aspects of obstructive sleep apnea syndrome (OSAS).[1] Both the European Respiratory Society and the European Sleep Research Society have noted the impact for research cooperative efforts of the database resource.[5]

History

2006 - 2010

In 2006 the European Sleep Apnea Database (ESADA) began as an initiative between 27 European sleep study facilities to combine information and compile it into one shared resource.[5][6] It was formed as part of the European Cooperation in Science and Technology (COST) Action B 26.[2][7] In addition to financial help from COST, the initiative received assistance from companies Philips Respironics and ResMed.[8] The database storing the association's resource information is located in Gothenburg, Sweden.[8] The group's goal was twofold: to serve as a reference guide to those researching sleep disorders, and to compile information about how different caregivers treat patients suffering from sleep apnea.[2][7]

5,103 patients were tracked from March 15, 2007 to August 1, 2009.[7] Data collected on these patients included symptoms suffered, medication, medical history, and sleep data, all inputted into an online format for further analysis.[7] Database researchers reported on their methodology and results in 2010 to the American Thoracic Society, on their observed findings regarding percentages of metabolic and cardiovascular impacts related to patients with obstructive sleep apnea.[9] The 2010 research resulted from collaboration between 22 study centres across 16 countries in Europe involving 27 researchers.[9] The primary participants who presented to the American Thoracic Society included researchers from: Sahlgrenska University Hospital, Gothenburg, Sweden; Technion – Israel Institute of Technology, Haifa, Israel; National TB & Lung Diseases Research Institute, Warsaw, Poland; CNR Institute of Biomedicine and Molecular, Palermo, Italy; Instituto Auxologico Italiano, Ospedale San Luca, Milan, Italy; and St. Vincent University Hospital, Dublin, Ireland.[9] Their results were published in 2010 in the American Journal of Respiratory and Critical Care Medicine.[9]

2011 - present

In 2011 there were 22 sleep disorder centres in Europe involved in the collaboration.[2][7] The group published research in 2011 on the percentage of patients suffering from sleep apnea that have obesity.[7] By 2012 the database maintained information on over 12,500 patients in Europe; it also contained DNA samples of 2,600 individuals.[8] ESADA was represented in 2012 at the 21st annual meeting of the European Sleep Research Society in Paris, France, and was one of four European Sleep Research Networks that held a session at the event.[10] Pierre Escourrou and Fadia Jilwan wrote a 2012 article for the European Respiratory Journal after studying data from ESADA involving 8,228 total patients from 23 different facilities.[11] They analyzed whether polysomnography was a good measure for hypopnea and sleep apnea.[11] Researchers from the department of pulmonary diseases at Turku University Hospital in Turku, Finland compared variations between sleep centres in the ESADA database and published their findings in the European Respiratory Journal.[12] They looked at the traits of 5,103 patients from 22 centres.[12] They reported on the average age of patients in the database, and the prevalence by region of performing sleep study with cardiorespiratory polygraphy.[12]

The database added a centre in Hamburg, Germany in 2013 managed by physician Holger Hein.[6] The group's annual meeting in 2013 was held in Edinburgh, United Kingdom and was ran by Renata Riha.[6] By March 2013, there were approximately 13,000 total patients being studied in the program, with about 200 additional patients being added into the database each month.[5] Analysis published by researchers from Italy and Sweden in September 2013 in the European Respiratory Journal analyzed if there was a correlation between renal function problems and obstructive sleep apnea.[13] They analyzed data from 17 countries in Europe representing 24 sleep centres and 8,112 total patients.[13] They tested whether patients of different types of demographics with other existing health problems had higher chance of kidney function problems, if they concurrently suffered from obstructive sleep apnea.[13]

In 2014, researchers released data studying 5,294 patients from the database compared prevalence of sleep apnea with increased blood sugar.[14] Their results were published in the European Respiratory Journal.[3][4] They studied glycated hemoglobin levels in the patients and compared them with measured severity in sleep apnea.[15] The researchers analyzed glycated hemoglobin levels among a class of individuals with less severe sleep apnea and those with a higher determined amount of sleep apnea problems.[14] As of 20 March 2014 the database included information on a total of 15,956 patients.[6] A 2014 article in the European Respiratory Journal drawing from the ESADA analyzed whether lack of adequate oxygen during a night's sleep was an indicator for high blood pressure.[16]

Reception

In the 2013 book Clinical Genomics: Practical Applications for Adult Patient Care, ESADA is said to be an example of the kind of initiative which affords an "excellent opportunity" for future collaborative research into genetic aspects of obstructive sleep apnea syndrome (OSAS).[1] Both the European Respiratory Society and the European Sleep Research Society have noted the impact for research cooperative efforts of the database resource.[5]

See also

Notes

  1. ^ a b c Murray 2013, p. 586.
  2. ^ a b c d e Hedner 2011, pp. 635-642.
  3. ^ a b Right Vision News 2014
  4. ^ a b Daily The Pak Banker 2014
  5. ^ a b c d ESRS Newsletter 2013
  6. ^ a b c d Grote 2014
  7. ^ a b c d e f Obesity, Fitness & Wellness Week 2011, p. 3.
  8. ^ a b c Grote May 2012, pp. 10-11.
  9. ^ a b c d Hedner 2010
  10. ^ ESRS Newsletter 2012, p. 8.
  11. ^ a b Escourrou 2012
  12. ^ a b c Saaresranta 2012
  13. ^ a b c Marrone 2013
  14. ^ a b Healthcare Purchasing News 2014, p. 16.
  15. ^ The Huffington Post 2014
  16. ^ Tkacova 2014, pp. 931-941

References

Further reading

  • "ESADA – European Sleep Apnea Database". Elicit. Elicit.se. 2014. Archived from the original on 18 October 2014. Retrieved 21 October 2014.
  • "Sleep Apnea Diagnostic and Therapeutic Devices Market Expected to Reach USD 6.43 Billion Globally in 2019: Transparency Market Research". India Pharma News. Contify.com. 12 May 2014 – via LexisNexis.
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