Talk:DNA

Compressed Representation

Does anyone have information about the recent news that DNA is in a compressed form and that the "junk" is actually part of the decompression mechanics? (kind of like a zip file) That would be an important addition to this article. Actually, it makes sense that the genome would be in the most compressed state to make reproduction efficient.

Acidity

Since this is Deoxyribonucleic acid, something should be said under "Properties" about its quite strong acidity. It is a polymer of phosphate esters, and "Since a monophosphate ester of this kind is a strong acid (pKa of 1.0), it will be fully ionized at the usual physiological pH (ca.7.4)." I.e. it will be in its conjugate base form in the cell. And the negative charge repels many nucleophiles that would otherwise attack it, so reducing the rate of nucleophilic hydrolysis by several orders of magnitude (these points sourced on this Michigan State University page Nucleic Acids.

Good idea! Added now. Blythwood (talk) 00:55, 30 June 2022 (UTC)

Semi-protected edit request on 12 October 2022

"a common way is the their melting temperature" 81.103.38.4 (talk) 09:43, 12 October 2022 (UTC)

 Done Terasail^[✉️] 11:35, 12 October 2022 (UTC)

Semi-protected edit request on 16 November 2022

Under "Base Pairing"

add: (or "Watson–Crick–Franklin") to "Watson-Crick base pair", to match current terminology in DNA science. Vecchionis (talk) 18:17, 16 November 2022 (UTC)

 Not done: please provide reliable sources that support the change you want to be made. Actualcpscm (talk) 23:09, 16 November 2022 (UTC)

Rosalind Franklin

Can we give Rosalinda Franklin a more prominent place in this article?

I think she may be mentioned in the first paragraph.

Kind regards, SeemGyro1 SeemGyro1 (talk) 09:30, 17 November 2022 (UTC)

 Not done This is an overarching article on DNA, the history of discovery of it is therefore a small part in such a fundamental and large topic, so it would give undue weight to include mention of those credited for the discovery in the lead of the article.|→ Spaully ^~talk~  10:03, 18 November 2022 (UTC)

She is mentioned alright in the History section.--–ꟼsyc^ho ㄈhi¢ken 😭 (talk) 14:40, 18 November 2022 (UTC)

I suppose you understand how to write articles better than me. I'm quite new here. SeemGyro1 (talk) 10:14, 28 November 2022 (UTC)

For the record, I'm inclined to think the amount of technical detail currently in the lead is excessive, and saying nothing in the lead about the history of our knowledge about DNA is a lack of balance.--Nø (talk) 17:01, 28 November 2022 (UTC)

I beckon this.

The author was an expert. That is the curse of our time. –ꟼsyc^ho ㄈhi¢ken 😭 (talk) 08:20, 4 February 2023 (UTC)

Non Canonical Bases – derived from Adenosine

Concerns this section: DNA#Listing of non-canonical bases found in DNA.

If Adenosine is a building block for RNA and Adenine only one of its components (the other being some ribose), can you please clarify why it is listed here alongside the other bases? Frankly, I believe that this is a mistake and it should be Adenine, but I cannot really know. TIA anyway. –ꟼsyc^ho ㄈhi¢ken 😭 (talk) 14:47, 18 November 2022 (UTC)

Adenine is the base. Adenosine is the base with the ribose sugar attached. Adenosine is in RNA. Deoxyadenosine is in DNA.

Is this supposed to explain why alongside the other bases, Adenosine is named instead of Adenine? I do not understand. The problem here is not Chemistry but language and the lack of. --–ꟼsyc^ho ㄈhi¢ken 😭 (talk) 20:56, 30 November 2022 (UTC)

Lacking a conclusion, I followed logic and looked up the topic elsewhere.

I cannot see the reason for the exception that is made for Adenine and – thus – modified the article accordingly.

You can still react and teach me something. No generalities, though. –ꟼsyc^ho ㄈhi¢ken 😭 (talk) 08:17, 4 February 2023 (UTC)

Editing.

Hey. Can I edit this page. Because I want to make it simpler. 129.126.35.127 (talk) 00:54, 16 May 2023 (UTC)