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'''Alison Barth''' is an American [[neuroscientist]] and the Maxwell H. and Gloria C. Connan Professor of Life Sciences, Biological Sciences and Neuroscience Institute at [[Carnegie Mellon University]]<ref>{{Cite web |last=University |first=Carnegie Mellon |title=Alison Barth - Neuroscience Institute - Carnegie Mellon University |url=https://www.cmu.edu/ni/people/faculty/abarth.html |access-date=2024-04-28 |website=www.cmu.edu |language=en}}</ref><ref name=":2">{{Cite web |date=2020-09-16 |title=Dr. Alison Barth |url=https://www.storiesofwin.org/profiles/2020/9/16/dr-alison-barth |access-date=2024-04-29 |website=Stories of WiN |language=en-US}}</ref><ref name=":3" />. She is the founder and principal investigator of Barth Lab, where the research focus is understanding how experience assembles and alters the properties of neural circuits in the cerebral cortex, in both typical and disordered states<ref name=":1">{{Cite web |title=Barth Lab |url=https://labs.bio.cmu.edu/barth/ |access-date=2024-04-28 |language=en-US}}</ref><ref name=":3" />.
'''Alison Barth''' is an American [[neuroscientist]] and the Maxwell H. and Gloria C. Connan Professor of Life Sciences, Biological Sciences and Neuroscience Institute at [[Carnegie Mellon University]]<ref>{{Cite web |last=University |first=Carnegie Mellon |title=Alison Barth - Neuroscience Institute - Carnegie Mellon University |url=https://www.cmu.edu/ni/people/faculty/abarth.html |access-date=2024-04-28 |website=www.cmu.edu |language=en}}</ref><ref name=":2">{{Cite web |date=2020-09-16 |title=Dr. Alison Barth |url=https://www.storiesofwin.org/profiles/2020/9/16/dr-alison-barth |access-date=2024-04-29 |website=Stories of WiN |language=en-US}}</ref><ref name=":3" /> and a fellow of the [[American Association for the Advancement of Science]]<ref name=":5" />.


== Early life and education ==
== Early life and education ==
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During her time at Stanford University, Barth developed and filed a provisional patent for the “fosGFP” mouse, a transgenic mouse that labels [[green fluorescent protein]] (GFP) expression [[in vivo]] and visualizes [[Neuron|neurons]] undergoing [[Neuroplasticity|plasticity]]<ref>{{Cite web |title=fosGFP Mouse: A Novel Transgenic Mouse for Identifying Subsets of Activated Cells {{!}} Explore Technologies |url=https://techfinder.stanford.edu/technology/fosgfp-mouse-novel-transgenic-mouse-identifying-subsets-activated-cells |access-date=2024-04-29 |website=techfinder.stanford.edu}}</ref><ref name=":2" />.
During her time at Stanford University, Barth developed and filed a provisional patent for the “fosGFP” mouse, a transgenic mouse that labels [[green fluorescent protein]] (GFP) expression [[in vivo]] and visualizes [[Neuron|neurons]] undergoing [[Neuroplasticity|plasticity]]<ref>{{Cite web |title=fosGFP Mouse: A Novel Transgenic Mouse for Identifying Subsets of Activated Cells {{!}} Explore Technologies |url=https://techfinder.stanford.edu/technology/fosgfp-mouse-novel-transgenic-mouse-identifying-subsets-activated-cells |access-date=2024-04-29 |website=techfinder.stanford.edu}}</ref><ref name=":2" />.


Barth then moved to [[Carnegie Mellon University]] in 2002, where she began teaching as a professor of Biological Sciences and Biomedical Engineering, eventually founding the Barth Lab<ref name=":2" /><ref name=":4" />. Founder and [[principal investigator]] for Barth lab, Barth leads her team and focuses on understanding how experience assembles and alters the properties of [[Neural circuit|neural circuits]] in the [[cerebral cortex]], in both typical and disordered states<ref name=":1" />.
Barth moved to [[Carnegie Mellon University]] in 2002, where she began her career as a professor of Biological Sciences and Biomedical Engineering. Currently, Barth's research focuses on understanding how the brain changes in response to experience, particularly in the context of learning and memory<ref name=":3" /><ref>{{Cite web |title=Reflecting causality in synaptic changes {{!}} Sainsbury Wellcome Centre |url=https://www.sainsburywellcome.org/web/qa/reflecting-causality-synaptic-changes |access-date=2024-04-29 |website=www.sainsburywellcome.org}}</ref>. She studies the [[Somatosensory system|somatosensory cortex]] of rodents, investigating how [[Synapse|synapses]] are altered as animals undergo different types of experiences<ref name=":3" />.

Currently, Barth's research focuses on understanding how the brain changes in response to experience, particularly in the context of learning and memory<ref name=":3" /><ref>{{Cite web |title=Reflecting causality in synaptic changes {{!}} Sainsbury Wellcome Centre |url=https://www.sainsburywellcome.org/web/qa/reflecting-causality-synaptic-changes |access-date=2024-04-29 |website=www.sainsburywellcome.org}}</ref>. She studies the [[Somatosensory system|somatosensory cortex]] of rodents, investigating how [[Synapse|synapses]] are altered as animals undergo different types of experiences<ref name=":3" />.

Barth's team has developed a tactile learning task for mice, where they stimulate the whiskers and then reward the animals with water to observe synaptic changes<ref name=":3" />. The goal is to identify the specific [[Neural network|neural networks]] that are altered as the animals learn these associations<ref name=":3" />. By pinpointing the synapses involved in these learned behaviors, Barth aims to uncover the neural circuits crucial for forming these associations, shedding light on the mechanisms underlying learning and memory<ref name=":3" />.


== Honors and Awards ==
== Honors and Awards ==
In 2012, she received the McKnight Foundation’s Memory and Cognitive Disorders Award<ref>{{Cite web |title=Awardees |url=https://www.mcknight.org/programs/the-mcknight-endowment-fund-for-neuroscience/memory-cognitive-disorders-awards/awardees/ |access-date=2024-04-29 |website=McKnight Foundation |language=en-US}}</ref>. In 2014, she received the Kaufman Grant to study neural communication in the [[cerebral cortex]]<ref>{{Cite web |title=2021 Kaufman Initiative Research Award - Zhao and Barth {{!}} Charles E. Kaufman Foundation |url=https://kaufman.pittsburghfoundation.org/awards/initiative/2021/molecularsynapticprofiling |access-date=2024-04-29 |website=kaufman.pittsburghfoundation.org |language=en}}</ref>.
In 2012, she received the McKnight Foundation’s Memory and Cognitive Disorders Award<ref>{{Cite web |title=Awardees |url=https://www.mcknight.org/programs/the-mcknight-endowment-fund-for-neuroscience/memory-cognitive-disorders-awards/awardees/ |access-date=2024-04-29 |website=McKnight Foundation |language=en-US}}</ref>. In 2014, she received the Kaufman Grant to study neural communication in the [[cerebral cortex]]<ref>{{Cite web |title=2021 Kaufman Initiative Research Award - Zhao and Barth {{!}} Charles E. Kaufman Foundation |url=https://kaufman.pittsburghfoundation.org/awards/initiative/2021/molecularsynapticprofiling |access-date=2024-04-29 |website=kaufman.pittsburghfoundation.org |language=en}}</ref>.


She was awarded the Society for Neuroscience’s Research Award for Innovation in Neuroscience and the Career Development Award in 2008, and she received the Humboldt Foundation’s Bessel Research Award as well in 2009<ref>{{Cite web |title=Prof. Dr. Alison L. Barth |url=https://www.humboldt-foundation.de/en/connect/explore-the-humboldt-network/singleview/1135186/prof-dr-alison-l-barth |access-date=2024-04-29 |website=www.humboldt-foundation.de |language=en}}</ref><ref>{{Cite web |last=University |first=Carnegie Mellon |title=Early Career Awards - Mellon College of Science - Carnegie Mellon University |url=http://www.cmu.edu/mcs/about/awards/faculty/early-career.html |access-date=2024-04-29 |website=www.cmu.edu |language=en}}</ref><ref>{{Cite web |title=Speakers |url=https://nm2.epfl.ch/nm2-2019/speakers/ |access-date=2024-04-29 |website=EPFL |language=en-GB}}</ref><ref>{{Cite web |title=Connect with Faculty Expert Alison Barth - News - Carnegie Mellon University |url=https://www.cmu.edu/news/experts/alison.barth |access-date=2024-04-29 |website=www.cmu.edu |language=en}}</ref><ref>{{Cite web |date=2024-04-20 |title=Carnegie Mellon University Celebrates Five Faculty Elected as 2023 AAAS Fellows |url=https://indiaeducationdiary.in/carnegie-mellon-university-celebrates-five-faculty-elected-as-2023-aaas-fellows/ |access-date=2024-04-29 |website=India Education {{!}} Latest Education News {{!}} Global Educational News {{!}} Recent Educational News |language=en-US}}</ref><ref name=":5">{{Cite web |last=Opdyke |first=Heidi |date=April 18, 2024 |title=Barth, Tetali Elected 2023 AAAS Fellows |url=http://www.cmu.edu/mcs/news-events/2024/0418_aaas-fellows-announcement.html |access-date=2024-04-29 |website=www.cmu.edu |language=en}}</ref>. Barth was elected as one of the 2023 fellows of the [[American Association for the Advancement of Science]]<ref name=":5" />.
She was awarded the Society for Neuroscience’s Research Award for Innovation in Neuroscience and the Career Development Award in 2008, and she received the Humboldt Foundation’s Bessel Research Award in 2009<ref>{{Cite web |title=Prof. Dr. Alison L. Barth |url=https://www.humboldt-foundation.de/en/connect/explore-the-humboldt-network/singleview/1135186/prof-dr-alison-l-barth |access-date=2024-04-29 |website=www.humboldt-foundation.de |language=en}}</ref><ref>{{Cite web |last=University |first=Carnegie Mellon |title=Early Career Awards - Mellon College of Science - Carnegie Mellon University |url=http://www.cmu.edu/mcs/about/awards/faculty/early-career.html |access-date=2024-04-29 |website=www.cmu.edu |language=en}}</ref><ref>{{Cite web |title=Speakers |url=https://nm2.epfl.ch/nm2-2019/speakers/ |access-date=2024-04-29 |website=EPFL |language=en-GB}}</ref><ref>{{Cite web |title=Connect with Faculty Expert Alison Barth - News - Carnegie Mellon University |url=https://www.cmu.edu/news/experts/alison.barth |access-date=2024-04-29 |website=www.cmu.edu |language=en}}</ref><ref>{{Cite web |date=2024-04-20 |title=Carnegie Mellon University Celebrates Five Faculty Elected as 2023 AAAS Fellows |url=https://indiaeducationdiary.in/carnegie-mellon-university-celebrates-five-faculty-elected-as-2023-aaas-fellows/ |access-date=2024-04-29 |website=India Education {{!}} Latest Education News {{!}} Global Educational News {{!}} Recent Educational News |language=en-US}}</ref><ref name=":5">{{Cite web |last=Opdyke |first=Heidi |date=April 18, 2024 |title=Barth, Tetali Elected 2023 AAAS Fellows |url=http://www.cmu.edu/mcs/news-events/2024/0418_aaas-fellows-announcement.html |access-date=2024-04-29 |website=www.cmu.edu |language=en}}</ref>.


== References ==
== References ==

Revision as of 15:26, 29 April 2024

Alison Barth is an American neuroscientist and the Maxwell H. and Gloria C. Connan Professor of Life Sciences, Biological Sciences and Neuroscience Institute at Carnegie Mellon University[1][2][3] and a fellow of the American Association for the Advancement of Science[4].

Early life and education

Alison Barth was born in the state of Maryland, but her family later moved to the states of Kansas, Wisconsin, and Ohio throughout her childhood[3]. She attended Brown University for her undergraduate education, where she received a Bachelor of Arts in Biology (1991)[5]. She then moved to the West Coast of the United States where she received her Ph.D. in Molecular and Cell Biology from the University of California, Berkeley (1997), and conducted her post-doctoral research in neurophysiology at Stanford University (2001)[5][2][6].

Research and Career

During her time at Stanford University, Barth developed and filed a provisional patent for the “fosGFP” mouse, a transgenic mouse that labels green fluorescent protein (GFP) expression in vivo and visualizes neurons undergoing plasticity[7][2].

Barth moved to Carnegie Mellon University in 2002, where she began her career as a professor of Biological Sciences and Biomedical Engineering. Currently, Barth's research focuses on understanding how the brain changes in response to experience, particularly in the context of learning and memory[3][8]. She studies the somatosensory cortex of rodents, investigating how synapses are altered as animals undergo different types of experiences[3].

Honors and Awards

In 2012, she received the McKnight Foundation’s Memory and Cognitive Disorders Award[9]. In 2014, she received the Kaufman Grant to study neural communication in the cerebral cortex[10].

She was awarded the Society for Neuroscience’s Research Award for Innovation in Neuroscience and the Career Development Award in 2008, and she received the Humboldt Foundation’s Bessel Research Award in 2009[11][12][13][14][15][4].

References

  1. ^ University, Carnegie Mellon. "Alison Barth - Neuroscience Institute - Carnegie Mellon University". www.cmu.edu. Retrieved 2024-04-28.
  2. ^ a b c "Dr. Alison Barth". Stories of WiN. 2020-09-16. Retrieved 2024-04-29.
  3. ^ a b c d "Episode 30: Alison Barth, PhD". Conjugate: Illustration and Science Blog. Retrieved 2024-04-28.
  4. ^ a b Opdyke, Heidi (April 18, 2024). "Barth, Tetali Elected 2023 AAAS Fellows". www.cmu.edu. Retrieved 2024-04-29.
  5. ^ a b "Alison L. Barth, Ph.D." www.isb.pitt.edu. Retrieved 2024-04-28.
  6. ^ Weigand, Jodi (February 6, 2010). "Newsmaker: Alison Barth". TribLive. Retrieved 2024-04-29.
  7. ^ "fosGFP Mouse: A Novel Transgenic Mouse for Identifying Subsets of Activated Cells | Explore Technologies". techfinder.stanford.edu. Retrieved 2024-04-29.
  8. ^ "Reflecting causality in synaptic changes | Sainsbury Wellcome Centre". www.sainsburywellcome.org. Retrieved 2024-04-29.
  9. ^ "Awardees". McKnight Foundation. Retrieved 2024-04-29.
  10. ^ "2021 Kaufman Initiative Research Award - Zhao and Barth | Charles E. Kaufman Foundation". kaufman.pittsburghfoundation.org. Retrieved 2024-04-29.
  11. ^ "Prof. Dr. Alison L. Barth". www.humboldt-foundation.de. Retrieved 2024-04-29.
  12. ^ University, Carnegie Mellon. "Early Career Awards - Mellon College of Science - Carnegie Mellon University". www.cmu.edu. Retrieved 2024-04-29.
  13. ^ "Speakers". EPFL. Retrieved 2024-04-29.
  14. ^ "Connect with Faculty Expert Alison Barth - News - Carnegie Mellon University". www.cmu.edu. Retrieved 2024-04-29.
  15. ^ "Carnegie Mellon University Celebrates Five Faculty Elected as 2023 AAAS Fellows". India Education | Latest Education News | Global Educational News | Recent Educational News. 2024-04-20. Retrieved 2024-04-29.
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