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== Health & Medical Applications ==
== Health & Medical Applications ==


Platinum nanoparticles is used in [[anti-aging]] [[medicines]]<ref> Complimentary Medicine, http://healthinfo.cedars-sinai.edu/library/healthguide/en-us/Cam/topic.asp?hwid=hn-1173001 </ref>, to delay the onset of [[aging]], slow down the side effects of aging<ref> Physiological Basis of Aging and Geriatrics, By Paola S. Timiras, p.26, Published 2003 Informa Health Care,http://en.wikipedia.org/wiki/Special:BookSources/0849309484 </ref> like [[aging]] associated [[diseases]] , to rejuvenate the [[human body]] [[cells]], to boost the body [[immune system]].
Platinum nanoparticles is used in [[anti-aging]] [[medicines]]<ref> Complimentary Medicine, http://healthinfo.cedars-sinai.edu/library/healthguide/en-us/Cam/topic.asp?hwid=hn-1173001 </ref>, to delay the onset of [[aging]], slow down the side effects of aging<ref> Physiological Basis of Aging and Geriatrics, By Paola S. Timiras, p.26, Published 2003 Informa Health Care,http://en.wikipedia.org/wiki/Special:BookSources/0849309484 </ref> like [[aging]] associated [[diseases]] , to rejuvenate the [[human body]] [[cells]], to boost the body [[immune system]]<ref>Beck, Gregory; Gail S. Habicht (November 1996). "Immunity and the Invertebrates, http://www.scs.carleton.ca/~soma/biosec/readings/sharkimmu-sciam-Nov1996.pdf</ref>.


Similar beneficial effects are said to be seen while using other daily products like [[Platinum Chewing Gum]] (also called as [[Nanogum]]), [[Platinum water]] (drinking water with platinum nanoparticles), [[Platinum Mouth Essence]] (Mouth wash with platinum nanoparticles) and various other products like [[cosmetics]]<ref> Keay Davidson. "FDA urged to limit nanoparticle use in anti-wrinkle cosmetics and sunscreens,http://www.sfgate.com/cgi-bin/article.cgi?file=/c/a/2006/05/17/MNGFHIT1161.DTL</ref> (supposedly to prevent [[wrinkles]]) etc.
Similar beneficial effects are said to be seen while using other daily products like [[Platinum Chewing Gum]] (also called as [[Nanogum]]), [[Platinum water]] (drinking water with platinum nanoparticles), [[Platinum Mouth Essence]] (Mouth wash with platinum nanoparticles) and various other products like [[cosmetics]]<ref> Keay Davidson. "FDA urged to limit nanoparticle use in anti-wrinkle cosmetics and sunscreens,http://www.sfgate.com/cgi-bin/article.cgi?file=/c/a/2006/05/17/MNGFHIT1161.DTL</ref> (supposedly to prevent [[wrinkles]]) etc.

Revision as of 15:16, 8 September 2008

Platinum Nanoparticles, are also called as “Platinum nano” or “Nano Platinum”. They are usually in the form of a suspension or colloid [1] of sub-micrometre-sized particles of platinum[2] in a fluid, usually water. A colloid is technically defined as particles which remain suspended without forming an ionic, or dissolved solution. The broader commercial definition of "colloidal platinum" includes products that contain various concentrations of ionic platinum, platinum colloids, ionic platinum compounds or platinum nanoparticles in purified water.

The Platinum Nanoparticles size ranges between 2-3 nanometres (2nm-3nm). Trillions of platinum Nanoparticles are suspended in the brownish red or black colored colloidal solution. Nanoparticles come in wide variety of shapes. Spheres, rods, cubes, and caps are some of the more frequently observed ones.

For centuries, the experimentation with various metals led to mastering and enhancements in various fields like medicine, metallurgy, engineering etc. Due to the unique anti-aging effects, anti free oxygen radicals properties or anti-Reactive oxygen species properties of the Platinum Nanoparticles, they are the subject of substantial research, with applications in a wide variety of areas, including Nanotechnology, medicine and the synthesis of novel materials with unique properties.

Synthesis

Platinum Nanoparticles[3] are fabricated by reduction of hexachloropatinate, including 0.02wt% of 90-130% of platinum during the determination of quantity. After dissolving hexachloropatinate, the solution is rapidly stirred, while a reducing agent is added. This causes Platinum ions to be reduced to neutral platinum atoms. As more and more of these platinum atoms form, the solution becomes supersaturated, platinum gradually starts to precipitate in the form of sub-nanometre particles. The rest of the platinum atoms that form stick to the existing particles, and, if the solution is stirred vigorously enough, the particles will be fairly uniform in size. Various procedures employed to attain platinum nanoparticles include heating, reflux, cooling, stirring, filtration and filling, examinations & tests and packaging. To prevent the particles from aggregating, some sort of stabilizing agent or stabilizer that sticks to the nanoparticle surface is usually added. They can be functionalized with various organic ligands to create organic-inorganic hybrids with advanced functionality.

History

The quest for the so-called” Elixir of life” by ancient alchemists to prolong youth & longevity, prevent aging and aging associated diseases, and rejuvenation of the human body and regain back the lost youth and maintain it for eternity, led to experimentation with various noble metals with known beneficial properties like Platinum, gold ,silver and even mercury. But unavailability of the means, safe route of administration eventually led to failures. With the strides in nanotechnology and platinum Nanoparticles, it is said to have reached a critical phase of human quest.

Current Research

Research in 21st century by Japanese scientists led by Prof.Miyamoto of the Department of Integrated Biosciences, Graduate school of Frontier Sciences, University of Tokyo, Japan,[4] resulted in the creation of platinum Nanoparticles of the size 2-3nm. They have also succeeded in improvisation and integration of platinum nanoparticles into the day to day commonly used products and medicines alike.

Mechanism of Action

Reactive oxygen species or free oxygen radicals causes aging, and aging associated diseases. Platinum Nanoparticles are termed to be very beneficial to the human physiology due to anti-reactive oxygen species (also known as anti-free oxygen radicals) properties. Platinum nanoparticles neutralize the harmful free oxygen radicals (or reactive oxygen species)in the body and prevent their detrimental actions within the human body.

Health & Medical Applications

Platinum nanoparticles is used in anti-aging medicines[5], to delay the onset of aging, slow down the side effects of aging[6] like aging associated diseases , to rejuvenate the human body cells, to boost the body immune system[7].

Similar beneficial effects are said to be seen while using other daily products like Platinum Chewing Gum (also called as Nanogum), Platinum water (drinking water with platinum nanoparticles), Platinum Mouth Essence (Mouth wash with platinum nanoparticles) and various other products like cosmetics[8] (supposedly to prevent wrinkles) etc.

See also

Comprehensive study of aging and free radicals

Platinum Chewing Gum

Colloidal_gold

Nanoparticles

Nanotechnology

References

  1. ^ Bernhard Wessling, Conductive Polymer / Solvent Systems: Solutions or Dispersions?, 1996, http://www2.ormecon.de/Research/soludisp/
  2. ^ Unknown Facts about Platinum, http://watches.infoniac.com/index.php?page=post&id=44
  3. ^ Creation of Platinum Nanoparticles , http://www.ias.ac.in/matersci/bmsdec2000/467.pdf
  4. ^ Graduate school of Frontier Sciences, University of Tokyo, Japan, http://www.ib.k.u-tokyo.ac.jp/ib-E/index.html
  5. ^ Complimentary Medicine, http://healthinfo.cedars-sinai.edu/library/healthguide/en-us/Cam/topic.asp?hwid=hn-1173001
  6. ^ Physiological Basis of Aging and Geriatrics, By Paola S. Timiras, p.26, Published 2003 Informa Health Care,http://en.wikipedia.org/wiki/Special:BookSources/0849309484
  7. ^ Beck, Gregory; Gail S. Habicht (November 1996). "Immunity and the Invertebrates, http://www.scs.carleton.ca/~soma/biosec/readings/sharkimmu-sciam-Nov1996.pdf
  8. ^ Keay Davidson. "FDA urged to limit nanoparticle use in anti-wrinkle cosmetics and sunscreens,http://www.sfgate.com/cgi-bin/article.cgi?file=/c/a/2006/05/17/MNGFHIT1161.DTL


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