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Research at home: this is an encyclopedia, not a venue for promotion of a cause
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:[[Talk:AIDS/Archive_18#FightAIDS.40Home_Project.3F|This has been proposed, and unsupported, before]]. Wikipedia is [[Wikipedia:NOT#Wikipedia_is_not_a_soapbox_or_means_of_promotion|not a place for promoting any cause, however laudable]]. If this project were to produce even one notable drug, then that might be worthy of inclusion - if supported by [[WP:MEDRS|reliable sources]] and truly [[WP:N|notable]]. -- [[User:Scray|Scray]] ([[User talk:Scray|talk]]) 22:55, 6 March 2010 (UTC)
:[[Talk:AIDS/Archive_18#FightAIDS.40Home_Project.3F|This has been proposed, and unsupported, before]]. Wikipedia is [[Wikipedia:NOT#Wikipedia_is_not_a_soapbox_or_means_of_promotion|not a place for promoting any cause, however laudable]]. If this project were to produce even one notable drug, then that might be worthy of inclusion - if supported by [[WP:MEDRS|reliable sources]] and truly [[WP:N|notable]]. -- [[User:Scray|Scray]] ([[User talk:Scray|talk]]) 22:55, 6 March 2010 (UTC)

My friend, there have already been successes, and published, in many areas of distributed computing. There is no "cause" being advocated here! This is virtual testing of molecules against disease. Do you know how the latest prime numbers were found? We are talking hard-core science. Seriously, you must be confusing this with something else. Thanks.

Revision as of 11:24, 7 March 2010

Former featured articleHIV/AIDS is a former featured article. Please see the links under Article milestones below for its original nomination page (for older articles, check the nomination archive) and why it was removed.
Main Page trophyThis article appeared on Wikipedia's Main Page as Today's featured article on June 15, 2006.
Article milestones
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March 12, 2006Peer reviewReviewed
April 8, 2006Featured article candidatePromoted
May 18, 2008Featured article reviewDemoted
Current status: Former featured article
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WikiProject iconThis article is within the scope of WikiProject Spoken Wikipedia, a collaborative effort to improve the coverage of articles that are spoken on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.

Gays

It should be noted that Aids is mostly prominent in the gay community. Although heterosexuals can get the disease the majority of those infected are gay or bi sexual. —Preceding unsigned comment added by 71.83.171.162 (talk) 01:30, 17 May 2009 (UTC)[reply]

If it were true, my anonymous friend, we would have noted it. However, it isn't, so it would be a very silly thing to "note". You may want to read the sections of the article on AIDS in Africa more closely. For future reference, comments on Wikipedia are generally left at the bottom of the talk pages, not the top, and signed by typing four tildes (~~~~) - Nunh-huh 03:15, 17 May 2009 (UTC)[reply]
Minor note, I've now moved this post to the bottom of the page. -Optigan13 (talk) 04:34, 17 May 2009 (UTC)[reply]
We're supposed to forget about the 8 million people in Africa with HIV. :P I guess all them are gay, too, right? Can we just delete this fucking section? I mean, really. Anonymous prick should move to Iran. --98.232.181.201 (talk) 03:43, 26 August 2009 (UTC)[reply]
If you were infected by a homosexual, that doesn't mean majority of the cases are. You should not let your personal experience interfere with reality. BytEfLUSh (talk) 22:44, 27 August 2009 (UTC)[reply]

You can get the disease from anyone, you don'thave to be gay nor bi sexual to catch it, seems like someone needs to read a little bit more into this disease!Shinea-sha (talk) 19:03, 17 November 2009 (UTC)[reply]

A while ago I tried to insert a small but significant statistic into an article about the connection between male homosexuality and HIV/AIDS in the United States but it was deleted twice.
It was direct from the CDC and PHAC, and stated that since active homosexual males are more than twice as likely to get HIV/AIDS yet account for only around 4% of the population, the disease was thus 50 times more prevalent among active homosexual men in the U.S. CDC officials even quoted this fact verbatim during at least one recent HIV Prevention Conference.
I cited everything with dozens of links and used neutral language, but my edits were removed due to "synthesis", i.e. I was apparently "drawing my own personal conclusions" from raw statistics, and it was thus "biased". So yes, there is a connection but according to Nunh-huh, "they" haven't noticed it yet. 174.20.71.154 (talk) 00:30, 23 December 2009 (UTC)[reply]

There is no denying the incidence as it pertains to risk, among the homosexual community specifically within the sphere of North America is significantly higher than any other demographic, again specifically within North America. That said, it's really important not to negate this important information; whether the impetus is fear of continuing to contribute to a stigma or fear-mongering, or any other motivation. Accurate information is pivotal in the continuing efforts to fight this deadly virus (ie. safe sex practices, etc. that didn't receive much attention before the AIDS epidemic/pandemic received notoriety and due attention). Ignoring or deleting accurate and well-documented information, as the above user has cited, regarding high-risk demographics doesn't serve to protect anyone. I hope they'll re-insert the information, and that other editors will try to see its importance without prejudice.Corymichael780 (talk) 19:52, 9 February 2010 (UTC)[reply]

This line is bullshit

"In the United States, young African-American women are also at unusually high risk for HIV infection. This is due in part to a lack of information about AIDS and a perception that they are not vulnerable, as well as to limited access to health-care resources and a higher likelihood of sexual contact with at-risk male sexual partners."

I read the source, complete bullshit. Stereotypical bullshit. Reads like; every African-American girl is a poor dumb tramp so of course they get aids more often.

Bullshit. —Preceding unsigned comment added by 97.91.148.119 (talk) 07:06, 27 November 2009 (UTC)[reply]

You may wish to read the reference: it points out several reasons why this is the case, none of which are your conclusion. If you have suggestions on how to make the article better, please share them. Unconstructive, reactive posts like yours offer nothing. TechBear | Talk | Contributions 14:17, 27 November 2009 (UTC)[reply]

I read the source and I am sharing my discontent with this statement. I think that the source is unconvincing and offers nothing that really enhances this article. The source appears unreliable. This worthless statement should be omitted, but I can only post nothings on the talk page as wiki is no longer free but is now as restricted as your viewpoint. —Preceding unsigned comment added by 97.91.148.119 (talk) 23:21, 27 November 2009 (UTC)[reply]

Personal attacks and incivility don't make for compelling suggestions. When I get a chance, I'll look at the source in question, maybe others will comment. -- Scray (talk) 23:35, 27 November 2009 (UTC)[reply]

U.S. patented cure for AIDS, U.S. patent #5676977

the fact that there is a cure for aids might be noted in the article as apparently its being suppressed

http://onlinejournal.com/artman/publish/article_2862.shtml

http://www.freepatentsonline.com/5676977.html

this should definitely be included


~~ —Preceding unsigned comment added by 68.63.197.186 (talk) 23:46, 9 December 2009 (UTC)[reply]

Method of curing AIDS with tetrasilver tetroxide molecular crystal devices

Abstract The diamagnetic semiconducting molecular crystal tetrasilver tetroxide (Ag.sub.4 O.sub.4) is utilized for destroying the AIDS virus, destroying AIDS synergistic pathogens and immunity suppressing moieties (ISM) in humans. A single intravenous injection of the devices is all that is required for efficacy at levels of about 40 PPM of human blood. The device molecular crystal contains two mono and two trivalent silver ions capable of "firing" electrons capable of electrocuting the AIDS virus, pathogens and ISM. When administered into the bloodstream, the device electrons will be triggered by pathogens, a proliferating virus and ISM, and when fired will simultaneously trigger a redox chelation mechanism resulting in divalent silver moieties which chelate and bind active sites of the entities destroying them. The devices are completely non-toxic. However, they put stress on the liver causing hepatomegaly, but there is no loss of liver function.

also note this site...this sounds phenomenal but the patent was filed and subjects have been given the shot, http://www.boydgraves.com/svcp/

~~ —Preceding unsigned comment added by 68.63.197.186 (talk) 23:52, 9 December 2009 (UTC)[reply]

As you've been told before, this isn't a cure for AIDS. That a patent was granted doesn't prove it "works". Much of the information on the websites you cite is not merely simply wrong, it's spectacularly wrong. - Nunh-huh 23:54, 9 December 2009 (UTC)[reply]
If anyone truly believes that technology exists to "fire" electrons from a silver ion to "electrocute" the AIDS virus in a "completely non-toxic" manner, then please contact me about about a large sum of Iraqi gold that I need your help in retrieving. :P In all seriousness, you might want to do some background research on Boyd Graves before citing his website in an encyclopedia. Oh, and here is some followup on Tetrasil, for the curious. Apparently it is at least useful as a pesticide to disinfect swimming pools... MastCell Talk 00:32, 10 December 2009 (UTC)[reply]

Spam and poorly sourced edits

As Scray observed in his reversion edit summary, the recent additions by Infinitesimus are poorly-sourced or unsourced. I would add that several of the statements made by the user are, at least according to current medical consensus, wrong. From the user's first contribution, through addition of apparent spam to main space in numerous articles, it would appear that Infinitesimus aims to add claims about an herbal remedy known as Dzherelo or ImmunoXel. Even if this remedy has been discussed in the primary literature (and the user has been notified of WP:MEDRS by several editors, see User talk:Infinitesimus), its addition to the main article on AIDS is a violation of WP:WEIGHT. Keepcalmandcarryon (talk) 02:17, 14 December 2009 (UTC)[reply]

I Have referred Keepcalm to my talk page, where I have reminded him of two things: 1. MEDRS does not require that ONLY secondary sources are used -- check through the AIDS pages and you will see many many primary sources used. Wikipedia medical entries would shrink to nothing if we follow Keepcalm's advice. 2. Deletion is NOT the way to edit contributions. Keepcalm would like to delete the corrections I have properly made regarding HIV and TB co-infection, including the severity of the problem as published by WHO and other "secondary" highly reliable sources. This is not your wikipedia, Keepcalm. Edit, don't delete. Thank you. Infinitesimus —Preceding unsigned comment added by Infinitesimus (talkcontribs) 02:53, 14 December 2009 (UTC)[reply]

I urge you to carefully consider KeepCalm's advice. While it is true that there are primary references in WP articles, our guidance (cited by KeepCalm) compels us to limit such references to the major conclusions of the primary reference, to avoid giving them undue weight, and generally to avoid things like phase II clinical trial results that are often overly optimistic. This is an encyclopedia, not a newspaper. BTW, deletion of inappropriate content is perfectly appropriate, within guidance of policies like WP:3RR etc. I also urge you to reconsider repeated insertions of material highlighting a particular product (i.e. ImmunoXel) because it gives me (and others, apparently) the impression that your view of this product might be non-neutral. -- Scray (talk) 04:02, 14 December 2009 (UTC)[reply]
Scray, you seem to understand this subject. In the section AIDS#Experimental_and_proposed_treatments, how do you possibly select abzyme and an single patient bone marrow transplant as worthy of the main AIDS page, and at the same time recommend deletion of the published Phase 2 positive results to which I referred? The two treatments I added, Immunoxel/Dzherelo for HIV/TB and Immunitor V1 for HIV cachexia, have been used in thousands of patients, well over 60,000 in the case of V1. I would propose a separate page for Experimental AIDS Treatments, where anything that does not have regulatory approval would be moved. Agreed? What I do not appreciate is wasting WP contributors' by simply deleting their work. --Infinitesimus (talk) 04:22, 14 December 2009 (UTC)[reply]
First, I do not determine the content on any WP page - this is a communal effort, based on consensus. You ask about two examples in this Talk page's article. In the case of abzyme, my own opinion is that's an unusual and interesting technology (an antibody-enzyme) and the entry does not name or promote a single product (I do not know whether that was the rationale was at the time it was added). For the bone marrow transplant, that garnered an unusual amount of attention, and was arguably the first cure of HIV infection. Of course, content in that space is fluid and may change as the field advances.
If you want to create a separate page on a subject of your choosing, you could draft it in userspace, e.g. in a sandbox associated with your username. It would be wise to get some input from other editors along the way, keeping in mind that any content will be evaluated based on adherence to applicable Wikipedia policy and guidelines, including WP:Notability. Also note that you do not "own" any content in Wikipedia, even that located in "your" userspace (more info here).
If you find deletion frustrating, please understand that it is a part of any editing process, and on WP one can reduce the risk of deletion by building consensus for changes that might be controversial. No matter what any of us do in anticipation of a change to WP, deletion is always a possibility. -- Scray (talk) 05:16, 14 December 2009 (UTC)[reply]
I too have concerns with these additions. The evidenced sites to support the claims have number of people in the trials around 50. I currently think that other than of interest with respect to research this is not notable.Doc James (talk · contribs · email) 17:45, 14 December 2009 (UTC)[reply]

Read the Cochrane paper before citing it

There is no greater disservice of wikipedia than editors mis-stating what a citation actually says. I am going to edit the herbal alternative section again to ensure that readers are not led to believe that the Cochrane review, in this case, was a large one -- it was not. Despite the great name of Cochrane, not all the reviews carry the same weight. Here are some points to consider: "Several randomized clinical trials testing the effect of herbal medicines" would lead anyone to think that the review included the majority, or at least a serious selection of herbal products used by the 60% of HIV patients who use them. The Cochrane in this case only reviewed 8 products! Only one trial per product! Small numbers of patients! Hello, Scray? Comment?--Infinitesimus (talk) 14:27, 17 December 2009 (UTC)[reply]

For Cochrane to include a trial it has to be of a certain quality. They than search the entire literature and include all these trial. The lack of trial means that there are not many trials of good quality.Doc James (talk · contribs · email) 14:56, 17 December 2009 (UTC)[reply]
Thanks Jmh and yes, I know how Cochrane works. That doesnt negate my points - only a few products reviewed, only one trial per product, only small numbers of patients.--Infinitesimus (talk) 15:29, 17 December 2009 (UTC)[reply]
I have corrected the wording. It was implied that Cochrane was just a collect of small trial and that there were large well done trials out there that were missed but were in the 2002 review.Doc James (talk · contribs · email) 15:36, 17 December 2009 (UTC)[reply]
Exactly. If there are only 8 well-designed randomized trials of alternative therapies for AIDS, that is not a flaw in the Cochrane review. It simply points up the lack of useful scientific evidence and research on the subject. Most herbal and alternative remedies have never been subjected to any sort of rigorous scientific evaluation, for a constellation of reasons which it's probably better not to argue over here. If we're reaching for the moral high ground, then I'm going to go with James and say that it's a disservice to the reader to imply that the Cochrane Library overlooked high-quality trials; they haven't. MastCell Talk 17:52, 17 December 2009 (UTC)[reply]
The only statement that is truthful is "The fact that a Cochrane review could only find some small clinical trials of 8 herbal products (which themselves were not adequately studied to make any conclusions) clearly indicates a lack of rigourous scientific evaluation, for a constellation of reasons." Any inference as to the lack of efficacy of ANY herbal or alternative treatments is spurious unless it cites a properly conducted clinical trial. Right? Keep it truthful.--Infinitesimus (talk) 18:19, 17 December 2009 (UTC)[reply]
Claiming things which have not been proven false must be true, and vice versa, is a logical fallacy. JoeSmack Talk 18:26, 17 December 2009 (UTC)[reply]
Not to mention directly at odds with 4 or 5 centuries of the scientific method, but who's counting... Do they still teach science in schools? You know, where you generate a hypothesis and then test it, rather than assume that your hypothesis is true and then demand that other people disprove it? The latter thought process seems to be the source of quite a few tedious arguments on Wikipedia. MastCell Talk 18:30, 17 December 2009 (UTC)[reply]

This edit and accompanying edit summary are not ideal. The edit summary claims that the Cochrane group "addressed 8 products, not herbals as a whole." That's wrong. They did, in fact, address herbals as a whole. They searched Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, LILACS, Science Citation Index, the Chinese Biomedical Database, TCMLARS; plus CISCOM, AMED, and NAPRALERT for all randomized, controlled clinical trials of herbal medicines. That is addressing herbals as a whole. MastCell Talk 18:37, 17 December 2009 (UTC)[reply]

Yes, that is proving two points: 1. there are only seven trials that met their criteria, and 2. looking at several products (all with numerous ingredients) they found suggestions of efficacy, but the numbers were small. Nothing else. --Infinitesimus (talk) 18:45, 17 December 2009 (UTC)[reply]
So to conclude "insufficient evidence to support the use" of alternative medicine. I am unsure what the issue is? We have no good evidence and without good evidence we should not recommend stuff. Doc James (talk · contribs · email) 18:57, 17 December 2009 (UTC)[reply]
It is the usual problem. Scientists say "no good evidence to show that herbal products change [endpoint]" and laypeople put it differently as "Scientists have demonstrated that herbal products have no ability to change [endpoint]". Be careful please. This is one of the obvious traps, that is sometimes well hidden in words. Readers of wikipedia cannot be expected to read between the lines to get the true outcome of scientific work. --Infinitesimus (talk) 19:07, 17 December 2009 (UTC)[reply]
We do not say that they do not work just that there is no evidence and no one is making a claim otherwise. It would be unwise to use something with no evidence when we have stuff that does have evidence of beneficial effect.Doc James (talk · contribs · email) 19:27, 17 December 2009 (UTC)[reply]

Vitamin supplementation

The importance of vitamins is understated currently. See for example any of the NLM-listed reviews on the subject eg http://www.ncbi.nlm.nih.gov/pubmed/17566547 . The no-citation negative comment in the vitamin section should be deleted. --Infinitesimus (talk) 19:16, 17 December 2009 (UTC)[reply]

That source does not deal with AIDS specifically, but with multivitamin supplementation in general. There are plenty of high-quality sources on multivitamin supplementation in HIV/AIDS. A reasonable starting point might be Marston et al. from NEJM, which was prompted by Fawzi et al., also in NEJM.

I would be fine with removing the statement of no benefit in adults with "adequate dietary nutritional intake", pending a specific source. It would be more accurate to say (as the WHO does here) that the primary thrust should be providing adequate dietary intake of calories and nutrients, and that multivitamin supplementation is a low-risk and perhaps useful addition in people who cannot achieve adequate nutritional intake. MastCell Talk 19:46, 17 December 2009 (UTC)[reply]

Ok, the deletion is a good idea, and as editors get a chance to review the literature, it is quite possible you will find plenty of example where various of the vitamins taken in excess of RDA minimums have significant, and important effects on various HIV/AIDS endpoints. This will come.--Infinitesimus (talk) 20:00, 17 December 2009 (UTC)[reply]

Selenium citation is misrepresented

Another complete misrepresentation of the citation in AIDS#Alternative_medicine. Hurwitz et al said that the selenium effect "remained significant after correcting for the effects of disease-related factors, including ART regimen and adherence". How does this possibly translate into what wikipedia says: "Selenium can be used as an adjunct therapy to standard antiviral treatments, but cannot itself reduce mortality and morbidity.[132]" I won't bother editing unless someone powerful agrees, since certain editors like repeatedly deleting things I write.--Infinitesimus (talk) 22:09, 20 December 2009 (UTC)[reply]

Is there any evidence that selenium alone (or selenium in combination, for that matter) can reduce mortality and morbidity? The Hurwitz trial doesn't provide any such evidence, as I'm sure you noticed when you read it. The Hurwitz trial used CD4 count and viral load as surrogate endpoints, and even then the difference between the selenium and placebo groups in those measures, while statistically significant, was extremely small and of questionable clinical importance. In any case, the trial made no pretensions of examining the effect of selenium supplementation on downstream morbidity or mortality endpoints. So could you elaborate a bit on why this is a "complete misrepresentation"? MastCell Talk 00:49, 21 December 2009 (UTC)[reply]
Well, this 2007 paper does seem to review the literature fairly completely when the authors say that "HIV studies have shown a relationship between a lower serum selenium level and a lower CD4 count, more opportunistic infections, faster disease progression, and greater HIV-related mortality". Regarding the numbers, the statistical significance is clearly stated, and the medical significance is also mentioned in this peer reviewed publication on a DBPC trial in a high impact journal. I don't have the experience to negate what they found: "The results support the use of selenium as a simple, inexpensive, and safe adjunct therapy in HIV spectrum disease."--Infinitesimus (talk) 01:35, 21 December 2009 (UTC)[reply]
Note the word "adjunct" in your final quote - this is reflected in the section in question: Selenium can be used as an adjunct therapy to standard antiviral treatments, but cannot itself reduce mortality and morbidity. The source you cite does not indicate that selenium by itself (i.e. in the absence of standard therapy) reduces morbidity or mortality. That seems balanced and well-supported by the literature cited. -- Scray (talk) 01:50, 21 December 2009 (UTC)[reply]
Cannot be used by itself? Wrong statement. The authors did not say what could or could not be used by itself. They merely observed that selenium was effective in the ways indicated and that its effectiveness was not dependent on whether ART was concomitantly used. It would be much more accurate to say what the authors found, that selenium supplementation helps in HIV treatment, as plain as day. No need to hide the result and say "Selenium can be used...", it should read as the authors concluded, as quoted above. Why misrepresent a good finding? --Infinitesimus (talk) 02:00, 21 December 2009 (UTC)[reply]
I think there are two misunderstandings here. First, the word "adjunct" refers to selenium used as an addition to other therapies. So when the quote says "a simple, inexpensive, and safe adjunct", they are saying exactly what Scray indicates. I'll assume that a misunderstanding of the word "adjunct" accounts for your misstatement about using selenium alone.

A slightly more sophisticated issue has to do with association (or correlation) vs. causation. There is evidence that lower levels of selenium are associated (correlated) with poorer outcomes in HIV/AIDS. That doesn't show causation, though. It may be that low selenium caused the poor outcomes, or it may be that low selenium levels are a by-product or marker for poor global nutritional status or other nutritional deficiencies that actually cause poor outcomes. The prospective randomized, controlled trial does try to answer the question of causation - but their answer is limited to saying that selenium caused a small improvement in viral load/CD4, not that selenium supplementation prevented clinical complications or death. MastCell Talk 05:53, 21 December 2009 (UTC)[reply]

AIDS and Homosexuals

The commonly-understood relationship, statistical or otherwise, between AIDS infection and homosexuality should be addressed. I appreciate that Wikipedians want to avoid appearing to endorse the misunderstanding that AIDS is a "gay disease", but the common perception that AIDS is an issue of particular interest to the gay community needs to be discussed, even if only to be refuted. Personally, I came to this article just now hoping that it would shed some light on the reason behind the connection. --MQDuck (talk) 23:56, 22 December 2009 (UTC)[reply]

Good luck with that, Duck. At the moment at least, the editors of this page are refusing to acknowledge raw statistics from the CDC and PHAC, the main disease authorities of the U.S. and Canada, respectively. Apparently any sort of connection with HIV/AIDS and homosexuality is "too hot to touch". 174.20.71.154 (talk) 00:35, 23 December 2009 (UTC)[reply]
If this page is a frequent target of the sort of people who like to say that AIDS is the result of the dirty lifestyle homosexuals supposedly live, I can understand if it's proved most practical to just avoid the issue of 'AIDS and gay people' altogether. But unless that's the case, I'd say it's a mistake to not address it. [Note: This comment was previously deleted for unclear reasons] --MQDuck (talk) 00:52, 23 December 2009 (UTC)[reply]
I believe it started out in the gay community and took some time to spread into heterosexuals. Also there are a number of pathophysiological and social considerations. The risk of transmission is 4% if you are the insertee in anal sex but only 1% if vaginal sex. There was also a famous airline employee who traveled around and had sex with everyone he could. He was homosexual. If this is not already in the article it should be. The risk of getting HIV if one is the male incerter is only 0.4%. The numbers are approximate from my school years.
The other issue is cultural and has to do with the distribution in the number of partners people of different genders have. If you wish to write about this issue I am sure it has a place. Cheers Doc James (talk · contribs · email) 04:33, 23 December 2009 (UTC)[reply]
I don't feel qualified to add such a section. Also, it should discuss the affect of AIDS on gay culture, not just throw out some statistics. Perhaps WikiProject LGBT studies can be recruited. --MQDuck (talk) 07:55, 23 December 2009 (UTC)[reply]
Well create something on your talk page. Let me know if you need help finding papers. And I can look it over once you have created something... Doc James (talk · contribs · email) 15:07, 23 December 2009 (UTC)[reply]

Please add the following info to the article....Repost...

Dietary concern and the disease

--124.78.212.48 (talk) 07:14, 19 January 2010 (UTC)[reply]

--124.78.212.48 (talk) 07:18, 19 January 2010 (UTC)[reply]

--124.78.212.48 (talk) 07:15, 19 January 2010 (UTC)[reply]

--124.78.212.48 (talk) 07:17, 19 January 2010 (UTC)[reply]

Disclaimer If the contents in the above links are involved in Glycemic index, Glycemic load and Insulin index, please ignore them as the measures have been questioned--222.64.218.235 (talk) 09:45, 20 January 2010 (UTC)[reply]

Research to AIDS vaccine

Research is being done to a AIDS vaccine (eg by the International AIDS Vaccine Initiative]], 2 key antibodies are discovered (GP9 and GP16) see http://www.sciencedaily.com/releases/2009/09/090903163730.htm

Terminology for rates

Hi everyone,

What is the consensus on Wikipedia for various terms associated with rates of AIDS infection?

In the news, I see the following terms:

  • HIV/AIDS prevalence rate:- fraction who have HIV circulating in their blood stream
  • HIV/AIDS transmission rate:- fraction of new cases of HIV infections
  • HIV/AIDS infection rate:- unclear whether this means "HIV/AIDS prevalence rate" or "HIV/AIDS transmission rate"
  • AIDS mortality rate:- fraction who die from AIDS or opportunistic diseases

I suggest that we match the terminology of a reliable source on direct quotes, but in paraphrases we avoid the unclear "HIV/AIDS infection rate".

--Kevinkor2 (talk) 03:54, 16 February 2010 (UTC)[reply]

Life expectancy without treatment

The article cites 3 different life expectancies for an AIDS patient without treatment, from 1 to 11 years. The difference in these figures ought to be explained. —Preceding unsigned comment added by 76.94.82.148 (talk) 19:44, 24 February 2010 (UTC)[reply]

The 9 to 11 year figure refers to the median survival from the time of initial infection with HIV, while the roughly one year survival is the period from the onset of the first AIDS defining illness (opportunistic infection or tumor).On A Leash (talk) 02:40, 2 March 2010 (UTC)[reply]
This means I could contract the infection with HIV, and pass it on for 8 to 10 years, before coming down with an AIDS defining illness. What a horrible disease! I hate diseases that have long subclinical infection periods.--Kevinkor2 (talk) 07:28, 2 March 2010 (UTC)[reply]


Research at home

It would be nice to point out that at least one distributed computing project (where private computer users can let their computers help find cures) is helping research new drugs before they are actually produced. This process saves time and money. See worldcommunitygrid.org

The research is public domain and non-profit. If people can help at home, why not? The computer does all the work. —Preceding unsigned comment added by 75.85.14.106 (talk) 21:22, 6 March 2010 (UTC)[reply]

This has been proposed, and unsupported, before. Wikipedia is not a place for promoting any cause, however laudable. If this project were to produce even one notable drug, then that might be worthy of inclusion - if supported by reliable sources and truly notable. -- Scray (talk) 22:55, 6 March 2010 (UTC)[reply]

My friend, there have already been successes, and published, in many areas of distributed computing. There is no "cause" being advocated here! This is virtual testing of molecules against disease. Do you know how the latest prime numbers were found? We are talking hard-core science. Seriously, you must be confusing this with something else. Thanks.