Loperamide/simethicone: Difference between revisions
drugbox, references |
Expanded article content |
||
| Line 7: | Line 7: | ||
<!--Clinical data--> |
<!--Clinical data--> |
||
| tradename = Imodium |
| tradename = Imodium Multi-Symptom Relief |
||
| Drugs.com = |
| Drugs.com = |
||
| MedlinePlus = |
| MedlinePlus = |
||
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
||
| pregnancy_US = |
| pregnancy_US = C |
||
| pregnancy_category= |
| pregnancy_category= |
||
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> |
||
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> |
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> |
||
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM --> |
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM --> |
||
| legal_US = |
| legal_US = OTC |
||
| legal_status = |
| legal_status = |
||
| routes_of_administration = |
| routes_of_administration = Oral |
||
<!--Identifiers--> |
<!--Identifiers--> |
||
| Line 29: | Line 29: | ||
}} |
}} |
||
'''Loperamide/simethicone''' is |
'''Loperamide/simethicone''' is combination [[medication]] marketed under the trade name '''Imodium Multi-Symptom Relief''' (formerly Imodium A-D Advanced) used to treat [[diarrhea]] and [[bloat|gas]] simultaneously. It is manufactured by the [[McNeil Laboratories#McNeil Consumer & Specialty medicals products|McNeil Consumer Healthcare Division]] of [[McNeil Laboratories|McNeil PPC, Inc]]. |
||
[[Loperamide]] is a [[Mu Opioid receptor|μ-opioid receptor]] [[agonist]] that works in the [[intestines]].<ref>[http://www.drugs.com/cons/imodium-a-d.html Imodium], drugs.com</ref> Although it is an [[opioid]], it has no effects on the [[central nervous system]]. It reduces diarrhea by slowing the transit time of contents through the intestinal tract thereby allowing more water to be reabsorbed from the [[intestinal lumen]]. |
|||
[[Simethicone]] reduces gas by allowing smaller gas bubbles to [[coalesce]] into larger bubbles in the intestinal tract, making them easier to pass. Simethicone is not absorbed from the gastrointestinal tract so there are no systemic side effects.<ref>[http://www.drugs.com/mtm/simethicone.html Simethicone], drugs.com</ref> |
|||
==Precautions== |
|||
Anti-diarrheal medications should be avoided if diarrhea is secondary to an [[infection]]. Avoid using such products in the presence of [[fever]], [[melena|black stools]], bloody stools, or stools containing [[mucus]].<ref>{{cite web|title=Imodium Product Page|url=http://www.imodium.com/products-imodium-multi-symptom-relief/index.jhtml|accessdate=6/19/2012}}</ref> |
|||
==References== |
==References== |
||
Revision as of 21:23, 19 June 2012
| Combination of | |
|---|---|
| Loperamide | Antidiarrheal |
| Simethicone | Gas reducer |
| Clinical data | |
| Trade names | Imodium Multi-Symptom Relief |
| Routes of administration | Oral |
| Legal status | |
| Legal status |
|
Loperamide/simethicone is combination medication marketed under the trade name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc.
Loperamide is a μ-opioid receptor agonist that works in the intestines.[1] Although it is an opioid, it has no effects on the central nervous system. It reduces diarrhea by slowing the transit time of contents through the intestinal tract thereby allowing more water to be reabsorbed from the intestinal lumen.
Simethicone reduces gas by allowing smaller gas bubbles to coalesce into larger bubbles in the intestinal tract, making them easier to pass. Simethicone is not absorbed from the gastrointestinal tract so there are no systemic side effects.[2]
Precautions
Anti-diarrheal medications should be avoided if diarrhea is secondary to an infection. Avoid using such products in the presence of fever, black stools, bloody stools, or stools containing mucus.[3]
References
- ^ Imodium, drugs.com
- ^ Simethicone, drugs.com
- ^ "Imodium Product Page". Retrieved 6/19/2012.
{{cite web}}: Check date values in:|accessdate=(help)
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |