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* [[elastic fibers]]
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IM SAD


== Disorders of connective tissue ==
== Disorders of connective tissue ==

Revision as of 12:45, 1 November 2006

Types of connective tissue

Connective tissue is one of the four types of tissue in traditional classifications (the others being epithelial, muscle, and nervous tissue.) It is largely a category of exclusion rather than one with a precise definition, but there are certain characteristics shared by all or most tissues in this category:

  • Involved in structure and support
  • Derived from mesoderm (there are exceptions)
  • Characterized largely by the traits of non-living tissue

Blood, cartilage, and bone are usually considered connective tissue, but because they differ so substantially from the other tissues in this class, the phrase "connective tissue proper" is commonly used to exclude those three. There is also variation in the classification of embryonic connective tissues; on this page they will be treated as a third and separate category.

Classification

Connective tissue proper

Embryonic connective tissues

Fiber types

Fiber types as follows:

IM SAD

Disorders of connective tissue

Various connective tissue conditions have been identified; these can be both inherited and environmental.

  • Marfan syndrome - a genetic disease causing abnormal fibrillin.
  • Scurvy - caused by a dietary deficiency in vitamin C, leading to abnormal collagen.
  • Ehlers-Danlos syndrome - a genetic disease causing progressive deterioration of collagens, with different EDS types affecting different sites in the body, such as joints, heart valves, organ walls, arterial walls, etc.
  • Osteogenesis imperfecta (brittle bone disease) - caused by insufficient production of good quality collagen to produce healthy, strong bones.
  • Fibrodysplasia ossificans progressiva - disease of the connective tissue, caused by a defective gene which turns connective tissue into bone.
  • Spontaneous pneumothorax - collapsed lung, believed to be related to subtle abnormalities in connective tissue.
  • Sarcoma - a neoplastic process originating in connective tissue.

See also