Talk:Dengvaxia controversy

Decontextualized numbers

"One thousand hospitalized"... but over what time period, and how does that compare to normal? PMID 27601519 (from just before the vaccine effort) says that ~842,000 cases of dengue happen each year there, and PMID 28093542 says ~794,000. With those numbers, it seems like only "one thousand hospitalized" could be a significant improvement. Do we have any sources that run proper comparisons? WhatamIdoing (talk) 18:33, 3 January 2019 (UTC)

I'm fairly confident that at this time, there are no MEDRS compliant sources that make such a comparison. So of course my own calculations don't belong in the article, but I did estimate this, digging into the papers you linked, also some papers they cited themselves. Summary, the childhood rate of dengue infection is about 2.5X the overall rate, out of a million kids you'd expect 10-20,000 infections, anywhere from 1500-4000 hospitalizations, and 10-20 deaths. That's just dengue. I also looked up gross mortality data from the Actuarial Society of the Philippines, which gave the all-cause death rate for children under 10 at about 1 per 4000. I haven't seen any sources on what the official cause of death was for the 100+ alleged dead victims (only the two who were confirmed to have died from dengue), but if that's just all or some of the kids who died since the vaccines were given, regardless of cause, that number is not unusual. Of course, in reality there are a shit-ton of variables that need to be accounted for, and hopefully something will appear in the literature that does just that.

There are a lot of recent publicans regarding Dengvaxia, but they don't consider recent clinical evidence from the Philippines, perhaps because that is not yet available. Leaving that aside, some useful sources I did find, PMID 6214489, "Considering dengue infection rates reach up to 90% in Philippines, majority of the school children who were inoculated with Dengvaxia will get the protective benefits of the vaccine. This projection, however, means that at least 10% or around 80 000 of those children who do not have a prior history of dengue infection are now at an increased risk of developing severe dengue", and PMID 29180056, for "hospitalization for severe dengue fever... in children younger than 9 years, the relative risk was 8.5". So this would suggest that you actually might not even notice the harm, if the harm is what would be expected from existing clinical data (the expected number of hospitalizations prevented and the expected number added nearly balance out, depending on vaccine effectiveness rate). Since the vast majority of dengue infections in the Philippines are not reported, it is likely unknowable for most of the vaccine recipients whether they had prior exposure, which would make the requisite subgroup analysis impossible. Someguy1221 (talk) 01:44, 22 January 2019 (UTC)

CRIMINAL CASE ON DENGVAXIA

Total Dengvaxia vaccinated done from March 2016 to November 2017 is 850,000.

Under PNoy –April, May & June 2016, while under President Duterte June 2016 to November 2017.

If this is correct, more children were vaccinated during President Duterte administration.

1. Why was only PNoy charge with criminal case and not President Duterte on this Dengvaxia vaccine case? 2. What countries in the whole world officially accept/allow Dengvaxia by the government? 3. Does Dengvaxia prove to be the cause of death of dengue?

REALME28 (talk) 05:10, 7 February 2019 (UTC)

Dates

Several sections of the article contain dates (e.g. February 5) with no year. This is likely to lead to confusion. Mock wurzel soup (talk) 23:26, 21 June 2019 (UTC)

"600 deaths"

New to wikipedia so not sure how to add to talk pages but:

Spurious interpretation of the text concerning "600 deaths". The statement was that 600 deaths were under investigation, this does not equate to the number of deaths that are caused by DENV. Thanks — Preceding unsigned comment added by 129.96.83.110 (talk) 00:35, 5 February 2020 (UTC)

"600 deaths" is not supported by any credible agency or health provider. the DOH has not linked a single death to the vaccine.