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This is an old revision of this page, as edited by 98.169.98.52 (talk) at 03:02, 11 April 2008 (→Dangers of Tonic Water). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

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Quinine dosage

In the United States, the Food and Drug Administration limits tonic water quinine to 83 ppm (83 mg per litre if calculated by mass), which is one-half to one-quarter the concentration used in therapeutic tonic.

Although it's clear that the concentration is lower, presumably drinking 2-4 times as much tonic water would give a larger dose of quinine? It's also not clear how much would have to be drunk in order to achieve a therapeutic dose. Or is there something wrong with my reasoning? Thanks.   — Lee J Haywood 09:20, 2 September 2006 (UTC)[reply]

My pharmacy offers quinidine sulfate, a generic drug, in 5 gr capsules and 260 mg tablets. You'd need to drink about 3 litres to get close to the tablet's dosage. Bill C

Please, don't mistake quinine and quinidine. They are structuraly very closely akin (one being an enantiomer, optical isomer of another); quinidine is used mainly as an antiarrhytmic drug (to control hearth rhytm disorders, arrhytmias), while quinine is nowadays used as a mild muscle relaxant (better said antispasmodic, preventing muscle cramps) and as a second-line antimalaric, if the malaria Plasmodiae are resistant against 1st line antimalarials. NB: It should be also noted, that quinine is quite cumulative and should be strictly avoided by pregnant women, because in large doses, it can cause an abortion and isn't generally safe in pregnancy (possibly teratogenic.)--84.163.127.5 (talk) 05:04, 29 January 2008 (UTC)[reply]

Strychnine

The german author Max Goldt reports that tonic water in the former GDR contained the toxin Strychnine instead of Quinine for it's lower price. Unfortunately I do not have any evidence for this claim apart from the essay "Wieder keine Harpunen, aber Gurke gegen Putenbuch".

—The preceding unsigned comment was added by 85.183.209.68 (talk) 11:09, 15 May 2007 (UTC).[reply]

Hello. There seems to be a little bit of disagreement concerning how to best link to Cocktails. So, here is a explanation. It should be linked to the actual title of the article ( [[Cocktail]] ) to avoid a redirect from occurring. Redirects do not take much time for Wikipedia's web servers to process, but all such redirects are cumulative, and should be avoided if possible and when it makes sense to do so. Using lower case in capitalization of the first character ( [[cocktail]] ) is fine, though if the article's title is two or more words, capitalization might matter (test it and see). Wikipedia articles are generally singular, so the links should be, too ( [[Cocktail]] not [[Cocktails]], which only works because someone manually created a redirect page with the "s" in it). There is a neat trick that Wikipedia uses for linking with plural words: just add the "s" (or "es") outside, but touching, the link ( [[Cocktail]]s ). This prevents the redirect, but the link looks correct to the reader. If it is necessary to use completely different wording in the link, then go ahead and add the "s" there ( several good [[Port wine|Ports]] ). I hope this clears up some of the confusion. :-)

In summary, within this article, please leave the link as [[cocktail]]s for maximum efficiency and readability. Thanks --Willscrlt (Talk·Cntrb) 22:59, 15 January 2007 (UTC)[reply]

Dangers of Tonic Water

The article mentions some of the dangers of tonic water, its degradation in sunlight to other compounds, its half-life, that its bitterness disappears after quinine has degraded, and that tonic water drinks should be discarded if no bitterness is detected. I performed a web search but was unable to find sources supporting this information. I was also unable to find any casual mention of it. Finally, I note that none of this information is in the article for quinine. The claims made in the article are very serious and should be verified before being published. For these reasons I will be removing the information from the article. --Ben James Ben 13:27, 23 September 2007 (UTC)[reply]

I also see that the section on quinine use in tonic water and alternatives such as quassia are also unsourced and possibly original research. I looked up the one reference listed, Academic Press Dictionary of Science and Technology, and found that it was merely a dictionary of scientific terms. It would not have the information mentioned in the article (beyond simple definitions). The other source is unpublished industry research. --Ben James Ben 14:00, 23 September 2007 (UTC)[reply]

--The cited article on the use of tonic water for muscle cramp relief actually mentions no such claim in the article itself. The testing of quinine for muscle cramp relief was performed through direct dosing, not drinking tonic water, and the point the article made was that the OTC quinine medication was banned by the FDA for very hazardous side effects. Why would someone even put this in here?

Brands

Below is the list of tonic water brands, removed from the main article. Having the list did not improve the article, and it was growing quite long.

Brands of tonic water:

--Ben James Ben 04:02, 9 October 2007 (UTC)[reply]

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